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R37DK048873

Funded outputs count: 74
Funder award ID: R37DK048873
OpenAlex ID: G5384500745
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress
2024 · Xu Xu, Arturo Mendoza, et al. · Science Signaling · 2
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Pharmacologic inhibition of lipogenesis for the treatment of NAFLD
2023 · William P. Esler, David E. Cohen · Journal of Hepatology · 111
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High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease
2023 · Christopher S. Krumm, Renée S. Landzberg, et al. · Molecular Metabolism · 4
Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis
2023 · Haiyue He, Akiko Sugiyama, et al. · Cancer Letters · 13
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes
2023 · Alfonso Rubio-Navarro, Nicolás Gómez-Banoy, et al. · Nature Cell Biology · 71
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Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice
2022 · Mohammad Kabbani, Eleftherios Michailidis, et al. · Cell Reports · 34
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Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP
2021 · Arturo Mendoza, Catherine Tang, et al. · Science Signaling · 37
Up‐regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice
2021 · Norihiro Imai, Hayley T. Nicholls, et al. · Hepatology · 11
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Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice
2021 · Christopher S. Krumm, Xu Xu, et al. · Journal of Biological Chemistry · 11
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Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice
2020 · Tibor I. Krisko, Hayley T. Nicholls, et al. · Cell Metabolism · 77
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Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins
2019 · Samir Softic, Jesse G. Meyer, et al. · Cell Metabolism · 225
Knockout of the X‐linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity
2019 · Daniel S. Sinden, Corey D. Holman, et al. · The FASEB Journal · 20
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity
2019 · Maria Plataki, LiChao Fan, et al. · JCI Insight · 35
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Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes
2019 · Saireudee Chaturantabut, Arkadi Shwartz, et al. · Gastroenterology · 108
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Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1–induced steatosis
2018 · Veronika Tillander, Akihiro Miniami, et al. · Journal of Biological Chemistry · 6
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Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis
2018 · Michele Alves‐Bezerra, Yingxia Li, et al. · Hepatology · 26
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Trimming the Fat: Acetyl‐CoA Carboxylase Inhibition for the Management of NAFLD
2018 · Norihiro Imai, David E. Cohen · Hepatology · 38
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Preemptive Activation of the Integrated Stress Response Protects Mice From Diet‐Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction
2018 · Xu Xu, Christopher Krumm, et al. · Hepatology · 43
Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice
2018 · Anna Staffas, Marina Burgos da Silva, et al. · Cell Host & Microbe · 143
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The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis
2018 · Yan-Xiao Ji, Zan Huang, et al. · Nature Medicine · 141
CalR: A Web-Based Analysis Tool for Indirect Calorimetry Experiments
2018 · Amir I. Mina, Raymond A. LeClair, et al. · Cell Metabolism · 464
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Triglyceride Metabolism in the Liver
2017 · Michele Alves‐Bezerra, David E. Cohen · Comprehensive physiology · 1,033
Regulation of fatty acid trafficking in liver by thioesterase superfamily member 1
2017 · Anal Desai, Michele Alves-Bezerra, et al. · Journal of Lipid Research · 12
Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress
2017 · Baran A. Ersoy, Kristal M. Maner-Smith, et al. · Journal of Clinical Investigation · 36
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Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling
2017 · Samir Softic, Manoj K. Gupta, et al. · Journal of Clinical Investigation · 347
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