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R01 DK069455

Funded outputs count: 32
Funder award ID: R01 DK069455
OpenAlex ID: G5468972572
Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development
2024 · Tayleur D. White, Abdulaziz Almutairi, et al. · Frontiers in Immunology · 3
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Ca2+-independent phospholipase A2β-derived PGE2 contributes to osteogenesis
2021 · William D. Hancock, Xiaoyong Lei, et al. · Prostaglandins & Other Lipid Mediators · 3
Lipid mediators and biomarkers associated with type 1 diabetes development
2020 · Alexander J. Nelson, Daniel J. Stephenson, et al. · JCI Insight · 28
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Macrophage polarization is linked to Ca2+-independent phospholipase A2β-derived lipids and cross-cell signaling in mice
2019 · Alexander J. Nelson, Daniel J. Stephenson, et al. · Journal of Lipid Research · 28
iPLA2β and its role in male fertility, neurological disorders, metabolic disorders, and inflammation
2018 · John Turk, Tayleur D. White, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 40
Analyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems
2016 · S.E. Barbour, S. Ramanadham · Methods in enzymology on CD-ROM/Methods in enzymology · 5
Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2)
2016 · Jason W. Ashley, William D. Hancock, et al. · Journal of Biological Chemistry · 46
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Calcium-independent phospholipases A2 and their roles in biological processes and diseases
2015 · Sasanka Ramanadham, Tomader Ali, et al. · Journal of Lipid Research · 195
Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5′-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells
2015 · Suzanne E. Barbour, Phuong T. Nguyen, et al. · Journal of Biological Chemistry · 23
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Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice
2014 · Robert N. Bone, Ying Gai, et al. · Diabetes · 49
Evidence of Contribution of iPLA2β-Mediated Events During Islet β-Cell Apoptosis Due to Proinflammatory Cytokines Suggests a Role for iPLA2β in T1D Development
2014 · Xiaoyong Lei, Robert N. Bone, et al. · Endocrinology · 29
Novel effects of Brefeldin A (BFA) in signaling through the insulin receptor (IR) pathway and regulating FoxO1-mediated transcription
2014 · Paulina Wyrozumska, Jason W Ashley, et al. · Cellular Logistics · 7
High Glucose Exposure Promotes Activation of Protein Phosphatase 2A in Rodent Islets and INS-1 832/13 β-Cells by Increasing the Posttranslational Carboxylmethylation of Its Catalytic Subunit
2013 · Daleep K. Arora, Baker Machhadieh, et al. · Endocrinology · 36
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Characterization of FKGK18 as Inhibitor of Group VIA Ca2+-Independent Phospholipase A2 (iPLA2β): Candidate Drug for Preventing Beta-Cell Apoptosis and Diabetes
2013 · Tomader Ali, George Kokotos, et al. · PLoS ONE · 35
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Genetic modulation of islet β-cell iPLA2β expression provides evidence for its impact on β-cell apoptosis and autophagy
2013 · Xiaoyong Lei, Robert N. Bone, et al. · Islets · 29
A link between endoplasmic reticulum stress‐induced β ‐cell apoptosis and the group VIA Ca 2+ ‐independent phospholipase A 2 (iPLA 2 β )
2010 · X. Lei, S. Zhang, et al. · Diabetes Obesity and Metabolism · 42
Evidence for proteolytic processing and stimulated organelle redistribution of iPLA2β
2010 · Haowei Song, Shunzhong Bao, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 32
HIV-protease inhibitors suppress skeletal muscle fatty acid oxidation by reducing CD36 and CPT1 fatty acid transporters
2010 · Scott R. Richmond, Michael J. Carper, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 35
Group VIA Ca2+-independent phospholipase A2 (iPLA2β) and its role in β-cell programmed cell death
2010 · Xiaoyong Lei, Suzanne E. Barbour, et al. · Biochimie · 52
Spontaneous Development of Endoplasmic Reticulum Stress That Can Lead to Diabetes Mellitus Is Associated with Higher Calcium-independent Phospholipase A2 Expression
2009 · Xiaoyong Lei, Sheng Zhang, et al. · Journal of Biological Chemistry · 61
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Skeletal Muscle Group VIA Phospholipase A2 (iPLA2β): Expression and Role in Fatty Acid Oxidation
2008 · Michael J. Carper, Sheng Zhang, et al. · Biochemistry · 23
Age-Related Changes in Bone Morphology Are Accelerated in Group VIA Phospholipase A2 (iPLA2β)-Null Mice
2008 · Sasanka Ramanadham, Kevin E. Yarasheski, et al. · American Journal Of Pathology · 64
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HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus
2008 · Michael J. Carper, W. Todd Cade, et al. · American Journal of Physiology-Endocrinology and Metabolism · 43
The Group VIA Calcium-Independent Phospholipase A2 Participates in ER Stress-Induced INS-1 Insulinoma Cell Apoptosis by Promoting Ceramide Generation via Hydrolysis of Sphingomyelins by Neutral Sphingomyelinase
2007 · Xiaoyong Lei, Sheng Zhang, et al. · Biochemistry · 83
Group VIA Phospholipase A2 Forms a Signaling Complex with the Calcium/Calmodulin-dependent Protein Kinase IIβ Expressed in Pancreatic Islet β-Cells
2004 · Zhepeng Wang, Sasanka Ramanadham, et al. · Journal of Biological Chemistry · 42
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