Analysis of human senescence-related T cells using cohort study
Description: We obtained flow-cytometry data on immune cells from more than 200 healthy individuals in a cohort of people in Nagahama city, and are analyzing a possible correlation between immune cell phenotypes and laboratory values. In addition, we succeeded in identifying new age-related T cell subset (CXCR3+ naive phenotype CD8 T cells) using thymectomy mouse model and confirmed the existence of CD8 T cells with similar phenotypic and functional properties in human.
Amount: ¥3,770,000
Funding type: research
Funder scheme: Grant-in-Aid for Challenging Exploratory Research
Start date: 2015-04-01
End date: 2018-03-31
Investigator: Yoko Hamazaki (lead)
Institution: Kyoto University
Funded outputs count: 8
Funder award ID: 15K15151
OpenAlex ID: G5517691439