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R01 DK059579

Funded outputs count: 53
Funder award ID: R01 DK059579
OpenAlex ID: G5576014698
IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes
2021 · Montgomery Blencowe, Allison Furterer, et al. · Diabetologia · 38
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Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes
2021 · Zhongying Wang, Tatyana Gurlo, et al. · Communications Biology · 44
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Low Grade Islet but Marked Exocrine Pancreas Inflammation in an Adult with Autoimmune Pre-Diabetes
2019 · Hiroshi Nomoto, Tatyana Gurlo, et al. · Case Reports in Endocrinology · 6
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Pancreatic alpha-cell mass across adult human lifespan
2019 · Abu Saleh Md Moin, Megan Cory, et al. · European Journal of Endocrinology · 18
Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes
2019 · Hiroshi Nomoto, Lina Pei, et al. · Diabetologia · 65
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IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function
2019 · Chiara Montemurro, Hiroshi Nomoto, et al. · Nature Communications · 85
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Pregnancy in human IAPP transgenic mice recapitulates beta cell stress in type 2 diabetes
2019 · Tatyana Gurlo, Sarah Kim, et al. · Diabetologia · 17
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In the setting of β-cell stress, the pancreatic duct gland transcriptome shows characteristics of an activated regenerative response
2018 · Alexandra E. Butler, David Kirakossian, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 7
Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment
2018 · Lucie Ruiz, Tatyana Gurlo, et al. · Cell Death and Disease · 20
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Increased Chromogranin A–Positive Hormone-Negative Cells in Chronic Pancreatitis
2018 · Abu Saleh Md Moin, Megan Cory, et al. · The Journal of Clinical Endocrinology & Metabolism · 19
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Cell cycle–related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line
2017 · Chiara Montemurro, Suryakiran Vadrevu, et al. · Cell Cycle · 43
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Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetes
2017 · Belinda Schludi, Abu Saleh Md Moin, et al. · JCI Insight · 26
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Pancreatic Nonhormone Expressing Endocrine Cells in Children With Type 1 Diabetes
2017 · Abu Saleh Md Moin, Megan Cory, et al. · Journal of the Endocrine Society · 12
Increased Proliferation of the Pancreatic Duct Gland Compartment in Type 1 Diabetes
2016 · Abu Saleh Md Moin, Peter C. Butler, et al. · The Journal of Clinical Endocrinology & Metabolism · 31
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β Cell–specific increased expression of calpastatin prevents diabetes induced by islet amyloid polypeptide toxicity
2016 · Tatyana Gurlo, Safia Costes, et al. · JCI Insight · 23
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Glucagon-like Peptide 1 Drugs as Second-line Therapy for Type 2 Diabetes
2016 · Peter C. Butler · JAMA Internal Medicine · 19
CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis
2016 · T. Gurlo, J. F. Rivera, et al. · Molecular Endocrinology · 43
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Membrane Curvature-sensing and Curvature-inducing Activity of Islet Amyloid Polypeptide and Its Implications for Membrane Disruption
2015 · Natalie C. Kegulian, Shalene Sankhagowit, et al. · Journal of Biological Chemistry · 43
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Type 2 diabetes as a protein misfolding disease
2015 · Abhisek Mukherjee, Diego Morales-Scheihing, et al. · Trends in Molecular Medicine · 342
Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes
2015 · Leslie S. Satin, Peter C. Butler, et al. · Molecular Aspects of Medicine · 238
Insulin-Degrading Enzyme Inhibition, a Novel Therapy for Type 2 Diabetes?
2014 · Safia Costes, Peter C. Butler · Cell Metabolism · 35
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Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity
2014 · Jacqueline F. Rivera, Safia Costes, et al. · Journal of Clinical Investigation · 214
UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells
2014 · Safia Costes, Tatyana Gurlo, et al. · Autophagy · 67
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Response to Comment on: Saisho et al. β-Cell Mass and Turnover in Humans: Effects of Obesity and Aging. Diabetes Care 2013;36:111–117
2013 · Yoshifumi Saisho, Alexandra E. Butler, et al. · Diabetes Care · 11
A Critical Analysis of the Clinical Use of Incretin-Based Therapies
2013 · Peter C. Butler, Michael Elashoff, et al. · Diabetes Care · 297
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