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Optimism and Exceptional Longevity

Description: STATEMENT OF RELEVANCE Building on prior work suggesting that optimism leads to more favorable health outcomes, we propose to examine the relationship of optimism to exceptional longevity (living to 85 year or older) and to identify mechanisms that can explain the health enhancing effects of optimism. Specifically, we will evaluate if optimism is associated with increased likelihood of engaging in healthy behaviors such as physical activity, is related to a slower rate of biologic aging (measured by telomere length and epigenetic clock), and leads to increased capacity to regulate emotions. Ultimately, by understanding mechanisms by which optimism may increase longevity we will expand knowledge of possible interventions to promote health in older individuals.
Funding type: research
Funder scheme: R01
Start date: 2016-09-01
End date: 2022-03-31
Investigator: FRANCINE GRODSTEIN
Institution: HARVARD SCHOOL OF PUBLIC HEALTH
Field: Psychology
Funded outputs count: 19
Funder award ID: R01AG053273
OpenAlex ID: G2806123384
2025 · Harold H Lee, Ruijia Chen, et al. · International Journal of Epidemiology · 12
2023 · Claudia Trudel-Fitzgerald, Lewina O. Lee, et al. · Anxiety Stress & Coping · 12
2023 · Harold H. Lee, Sakurako S. Okuzono, et al. · Social Psychiatry and Psychiatric Epidemiology · 9
2022 · Cuicui Wang, Dawn L. DeMeo, et al. · Psychosomatic Medicine · 6
2022 · Hayami K. Koga, Claudia Trudel‐Fitzgerald, et al. · Journal of the American Geriatrics Society · 25
2022 · Maude Wagner, Anne-Josée Guimond, et al. · Innovation in Aging · 17
2022 · Sakurako S. Okuzono, Koichiro Shiba, et al. · Journal of Happiness Studies · 3
2022 · Lewina O Lee, Francine Grodstein, et al. · The Journals of Gerontology Series B · 18
2021 · Peter James, Claudia Trudel-Fitzgerald, et al. · JMIR Formative Research · 1
2021 · Harold H. Lee, Laura D. Kubzansky, et al. · Preventive Medicine · 10
2020 · Harold H. Lee, Sakurako S. Okuzono, et al. · Psychoneuroendocrinology · 3
2019 · Eric S. Kim, Hilary A. Tindle, et al. · Psychosomatic Medicine · 11
2019 · Lewina O. Lee, Peter James, et al. · Proceedings of the National Academy of Sciences · 195
2019 · Eric S. Kim, Kelvin Fong, et al. · Aging · 9
2019 · Claudia Trudel-Fitzgerald, Peter James, et al. · Preventive Medicine · 65
2019 · Eric S Kim, Peter James, et al. · American Journal of Epidemiology · 121
2018 · Peter James, Eric S. Kim, et al. · American Journal of Preventive Medicine · 121
1984 · Susan S. Golden, Louis A. Sherman · OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
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