Fundamental studies for application of small linear accelerator to in-hospital BNCT
Description: We conducted a series of fundamental experiments using a small neutron source based on a linear accelerator for in-hospital boron neutron capture therapy (BNСT). We have also developed a new patient positioning system that allows easy and correct orientation of the therapeutic target on the patient's head using real-time laser beams in combination with a treatment planning system called Tsukuba Plan. We have also accomplished preclinical studies using new promising boron compound candidates, alpha-d-mannopyranoside and eBNPs. These two stable compounds have shown proper tumoricidal effects.
Amount: ¥17,030,000
Funding type: research
Funder scheme: Grant-in-Aid for Scientific Research (B)
Start date: 2018-04-01
End date: 2022-03-31
Investigator: Akira Matsumura
Institution: University of Tsukuba
Funded outputs count: 10
Funder award ID: 18H02909
OpenAlex ID: G5692443251