Award

22H02809

Funder: Japan Society for the Promotion of Science

Funded outputs count: 7

Funder award ID: 22H02809

OpenAlex ID: G5704117428

A Sensitive, Specific, and Cost-Effective Lauroylation-Assisted Workflow for Profiling Peptide-Level Protease Specificity Using Proteomic Identification of Cleavage Sites (PICS), with Applicability to Protein-Level N-Terminomics

2026 · Hiroki Okanishi, Isayuki Uno, et al. · Journal of Proteome Research

Pharmacological and structural insights into nanvuranlat, a selective LAT1 (SLC7A5) inhibitor, and its N-acetyl metabolite with implications for cancer therapy

2025 · Chunhuan Jin, Xinyu Zhou, et al. · Scientific Reports · 6

Amino acid transporter LAT1 is expressed on cancer cell-derived exosomes with potential as a diagnostic and prognostic biomarker

2024 · Yumiao Liu, Ryuichi Ohgaki, et al. · Scientific Reports · 8

LAT1 expression in colorectal cancer cells is unresponsive to HIF-1/2α accumulation under experimental hypoxia

2024 · Ryuichi Ohgaki, Yuma Hirase, et al. · Scientific Reports · 3

Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells

2024 · Yu Ma, Suguru Okuda, et al. · Journal of Pharmacological Sciences · 5

Structure–activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)

2024 · Sihui Chen, Chunhuan Jin, et al. · Scientific Reports · 18

Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models

2023 · Zitong Shi, Kazuko Kaneda-Nakashima, et al. · Scientific Reports · 22