Sexual dimorphism of thymic epithelial cells
Description: T lymphocytes are educated in the thymus where they learn to differentiate self (our normal cells) from non-self (infected or neoplastic cells). We have found that sex hormones have a major impact on thymic function. We now wish to understand the mechanistic basis for this sexual dimorphism because it is probably responsible, at least in part, for the well-recognized sex differences in susceptibility to infections and autoimmune diseases.
Amount: CA$150,000
Funding type: research
Funder scheme: Catalyst Grant: Integrating Sex as a Variable in Biomedical Research
Start date: 2018-04-01
End date: 2020-03-31
Investigator: Claude Perreault
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Funded outputs count: 1
Funder award ID: 158605_1
OpenAlex ID: G5724066678