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K99 DK080774

Funded outputs count: 21
Funder award ID: K99 DK080774
OpenAlex ID: G5724780428
Pharmacogenomic Variants May Influence the Urinary Excretion of Novel Kidney Injury Biomarkers in Patients Receiving Cisplatin
2017 · Cara Chang, Yichun Hu, et al. · International Journal of Molecular Sciences · 38
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In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants
2017 · Xia Wen, Melanie S. Joy, et al. · Pharmaceutical Research · 23
Xenobiotic transporters and kidney injury
2017 · Blessy George, Dahea You, et al. · Advanced Drug Delivery Reviews · 142
Profiling of Kidney Injury Biomarkers in Patients Receiving Cisplatin: Time‐dependent Changes in the Absence of Clinical Nephrotoxicity
2016 · B George, X Wen, et al. · Clinical Pharmacology & Therapeutics · 48
Activation of NRF2 Signaling in HEK293 Cells by a First-in-Class Direct KEAP1-NRF2 Inhibitor
2015 · Xia Wen, Gabriell Thorne, et al. · Journal of Biochemical and Molecular Toxicology · 27
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Transgenic Expression of the Human MRP2 Transporter Reduces Cisplatin Accumulation and Nephrotoxicity in Mrp2-Null Mice
2014 · Xia Wen, Brian Buckley, et al. · American Journal Of Pathology · 61
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Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection)
2013 · Meeghan A. O'Connor, Petra Koza-Taylor, et al. · Toxicology and Applied Pharmacology · 27
Assessment of Drug Transporter Function Using Fluorescent Cell Imaging
2013 · Kristin M. Bircsak, Christopher J. Gibson, et al. · Current Protocols in Toxicology · 28
Hepatic and renal Bcrp transporter expression in mice treated with perfluorooctanoic acid
2013 · Lobna M. Eldasher, Xia Wen, et al. · Toxicology · 29
Pregnancy Represses Induction of Efflux Transporters in Livers of Type I Diabetic Mice
2013 · Lauren M. Aleksunes, Jialin Xu, et al. · Pharmaceutical Research · 12
Alteration of the Expression of Pesticide-Metabolizing Enzymes in Pregnant Mice: Potential Role in the Increased Vulnerability of the Developing Brain
2012 · Marie C. Fortin, Lauren M. Aleksunes, et al. · Drug Metabolism and Disposition · 23
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Regulation of Hepatic Phase II Metabolism in Pregnant Mice
2012 · Xia Wen, Ajay C. Donepudi, et al. · Journal of Pharmacology and Experimental Therapeutics · 27
Inflammatory Regulation of ATP Binding Cassette Efflux Transporter Expression and Function in Microglia
2012 · Christopher J. Gibson, Muhammad M. Hossain, et al. · Journal of Pharmacology and Experimental Therapeutics · 68
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Endocrine and metabolic regulation of renal drug transporters
2012 · Lindsay L. Yacovino, Lauren M. Aleksunes · Journal of Biochemical and Molecular Toxicology · 31
Down-Regulation of Brush Border Efflux Transporter Expression in the Kidneys of Pregnant Mice
2012 · Lindsay L. Yacovino, Christopher J. Gibson, et al. · Drug Metabolism and Disposition · 17
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Renal efflux transporter expression in pregnant mice with Type I diabetes
2012 · Lindsay L. Yacovino, Lauren M. Aleksunes · Toxicology Letters · 12
Coordinated Regulation of Hepatic Phase I and II Drug-Metabolizing Genes and Transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-Null Mice
2012 · Lauren M. Aleksunes, Curtis D. Klaassen · Drug Metabolism and Disposition · 257
Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity
2010 · Lauren M. Aleksunes, Michael J. Goedken, et al. · Journal of Pharmacology and Experimental Therapeutics · 178
Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation
2010 · Curtis D. Klaassen, Lauren M. Aleksunes · Pharmacological Reviews · 807
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Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice
2010 · Lauren M. Aleksunes, Scott A. Reisman, et al. · Journal of Pharmacology and Experimental Therapeutics · 106
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Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers
2009 · L. M. Aleksunes, R. L. Yeager, et al. · Xenobiotica · 23
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