BLI-4 acts in lifespan extension of C. elegans cultured in axenic medium.
Description: Lifespan extension by means of dietary restriction (DR) is evolutionarily conserved. Axenic (sterile) dietary restriction (ADR) in the nematode C. elegans doubles lifespan and is dependent on BLI-4. We will investigate tissue and isoform specificity in which BLI-4 acts in this lifespan extension. Also, the spatio-temporal analysis of age-related tissue deterioration will be performed in ADR-treated worms.
Funder: Vlaamse regering
Funding type: fellowship
Funder scheme: BOF - doctoral mandates
Start date: 2024-02-01
End date: 2024-07-31
Investigator: Bart Braeckman
Institution: UGent
Funded outputs count: 0
Funder award ID: BOF24/CDV/005
OpenAlex ID: G5727984701