Award

Plasma proteomic signatures of physical activity and Alzheimer's disease and related dementias

Description: PROJECT NARRATIVE This research will apply and compare machine-learning methods to derive plasma proteomic signatures of physical activity and examine them in relation to ADRD, yielding insight into the molecular mechanisms and biological processes through which physical activity may delay or prevent ADRD. This research may result in proteomic biomarkers of physical activity that measure the effect of physical activity to delay or prevent ADRD and suggest potential proteomic intervention targets.
Funding type: career_development
Funder scheme: K99
Start date: 2023-09-01
End date: 2025-08-31
Investigator: STEVE NGUYEN
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Funded outputs count: 15
Funder award ID: K99AG082863
OpenAlex ID: G3219071764
2026 · Andrea Z LaCroix, Bowei Zhang, et al. · The Journals of Gerontology Series A
2025 · Bowei Zhang, Linda K. McEvoy, et al. · Alzheimer s & Dementia · 7
2025 · Laura B. Harrington, Kara L. Cushing-Haugen, et al. · Journal of Thrombosis and Haemostasis · 5
2024 · Natalie M. Yarish, Alexander Ivan B. Posis, et al. · Journal of Women & Aging · 7
2024 · Steve Nguyen, John Bellettiere, et al. · Journal of the American Heart Association · 17
2024 · Michael J. LaMonte, Andrea Z. LaCroix, et al. · JAMA Cardiology · 29
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