Ketone ester intervention in alcohol use disorder
Description: 8. PROJECT NARRATIVE The proposed research is relevant to public health because understanding the effects of chronic alcohol use on brain functioning, withdrawal, craving, sleep, and alcohol consumption may help to prevent alcohol use disorder, which affects 10% of Americans throughout their life. Moreover, the proposed study directly aims to alleviate alcohol withdrawal symptoms during detoxification, which are distressing and can be life threatening. The proposed study is in line with NIAAA’s mission because it generates fundamental knowledge on the potentially beneficial effects of a novel ketogenic diet intervention on brain energetics, and alcohol withdrawal during alcohol detoxification, to improve the diagnosis, treatment, and ultimately the prevention of alcoholism.
Funding type: research
Funder scheme: R00
Start date: 2019-04-25
End date: 2024-08-31
Investigator: CORINDE E WIERS
Institution: UNIVERSITY OF PENNSYLVANIA
Topic: Diet and metabolism studies
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 30
Funder award ID: R00AA026892
OpenAlex ID: G10695739