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Genetic control mechanisms of long-term neuronal survival

Description: PROJECT NARRATIVE Aberrant neuronal cell death during brain development or throughout lifespan can lead to neurodevelopmental or neurodegenerative diseases. Knowledge about precise control of neuronal survival is essential to dissecting the underlying pathogenic mechanisms. Our proposed studies will provide novel insights to how neuronal survival is mediated by alternative mRNA splicing and to the etiology of neurological disorders.
Funding type: research
Funder scheme: R01
Start date: 2024-07-01
End date: 2029-04-30
Investigator: SIKA ZHENG
Institution: UNIVERSITY OF CALIFORNIA RIVERSIDE
Funded outputs count: 10
Funder award ID: R01NS139485
OpenAlex ID: G9000866028
2025 · Wei Jiang, Sika Zheng, et al. · Nature Communications · 7
2025 · Qingyang Yin, Liang Chen · bioRxiv (Cold Spring Harbor Laboratory) · 1
2024 · Lin Lin, Naoto Kubota, et al. · Molecular Cell · 2
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