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Strategies to Enhance Lymphoid Recovery After Radiation-Induced Injury

Funding type: research
Funder scheme: R01
Start date: 2008-06-25
End date: 2013-05-31
Investigator: MARCEL R M VAN DEN BRINK
Institution: SLOAN-KETTERING INST CAN RESEARCH
Funded outputs count: 66
Funder award ID: R01AI080455
OpenAlex ID: G3303659782
Die Rolle zytosolischer Nukleinsäurerezeptoren bei Strahlentherapie- oder Chemotherapie-induziertem intestinalen Gewebeschaden und der Graft-versus-host disease
2019 · Julius Fischer · mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)
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Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice
2018 · Anna Staffas, Marina Burgos da Silva, et al. · Cell Host & Microbe · 144
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Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
2018 · Tobias Wertheimer, Enrico Velardi, et al. · Science Immunology · 136
Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury
2018 · Enrico Velardi, Jennifer J Tsai, et al. · Nature Medicine · 44
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium
2017 · Yu Matsuzawa-Ishimoto, Yusuke Shono, et al. · The Journal of Experimental Medicine · 293
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Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease
2017 · Jarrod A. Dudakov, Anna M. Mertelsmann, et al. · Blood · 78
RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury
2017 · Julius C. Fischer, Michael Bscheider, et al. · Science Translational Medicine · 142
Late Effects of Exposure to Ionizing Radiation and Age on Human Thymus Morphology and Function
2017 · Reiko Ito, Laura P. Hale, et al. · Radiation Research · 38
Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation
2017 · Jonathan U. Peled, Sean M. Devlin, et al. · Journal of Clinical Oncology · 325
Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation
2017 · Daniela Weber, Robert R. Jenq, et al. · Transplantation and Cellular Therapy · 246
Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus
2016 · Mohammed S Chaudhry, Enrico Velardi, et al. · The Journal of Immunology · 119
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
2016 · Yusuke Shono, Melissa D. Docampo, et al. · Science Translational Medicine · 594
Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms
2016 · Emma Mitchell, Shifra L. Klein, et al. · Nature Communications · 39
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Thymus: the next (re)generation
2016 · Mohammed S. Chaudhry, Enrico Velardi, et al. · Immunological Reviews · 183
Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
2016 · Yusuke Shono, Andrea Z. Tuckett, et al. · Cancer Research · 39
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Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
2015 · Caroline A. Lindemans, Marco Calafiore, et al. · Nature · 1,124
Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer
2015 · Katharina Kreymborg, Stefan Haak, et al. · Cancer Immunology Research · 40
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Sex steroid ablation: an immunoregenerative strategy for immunocompromised patients
2015 · E Velardi, J A Dudakov, et al. · Bone Marrow Transplantation · 29
Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease
2015 · Robert R. Jenq, Ying Taur, et al. · Transplantation and Cellular Therapy · 750
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Interleukin-22: Immunobiology and Pathology
2015 · Jarrod A. Dudakov, Alan M. Hanash, et al. · Annual Review of Immunology · 907
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Sex steroid blockade enhances thymopoiesis by modulating Notch signaling
2014 · Enrico Velardi, Jennifer J. Tsai, et al. · The Journal of Experimental Medicine · 122
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Autophagy Gene Atg16l1 Prevents Lethal T Cell Alloreactivity Mediated by Dendritic Cells
2014 · Vanessa M. Hubbard-Lucey, Yusuke Shono, et al. · Immunity · 102
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Nfil3 is crucial for development of innate lymphoid cells and host protection against intestinal pathogens
2014 · Theresa L. Geiger, Michael C. Abt, et al. · The Journal of Experimental Medicine · 269
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WNT Signaling Suppression in the Senescent Human Thymus
2014 · Sara Ferrando-Martínez, Ezequiel Ruiz-Mateos, et al. · The Journals of Gerontology Series A · 34
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Image-guided intrathymic injection of multipotent stem cells supports lifelong T-cell immunity and facilitates targeted immunotherapy
2014 · Andrea Z. Tuckett, Raymond H. Thornton, et al. · Blood · 20
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