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星形胶质细胞IL-17A/Act1通路在老年小鼠术后认知功能障碍的作用及机制研究

Amount: ¥340,000
Funding type: grant
Funder scheme: 地区科学基金项目
Start date: 2017-01-01
End date: 2021-12-31
Investigator: 福洲 华
Institution: 南昌大学
Funded outputs count: 18
Funder award ID: 81760261
OpenAlex ID: G5910083166
Minocycline alleviates lipopolysaccharide-induced cardiotoxicity by suppressing the NLRP3/Caspase-1 signaling pathway
2024 · Huijuan Li, Xiaozhong Li, et al. · Scientific Reports · 5
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Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway
2024 · Fenfang Zhan, Yao Dong, et al. · Aging · 10
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DNA damage response and GATA4 signaling in cellular senescence and aging-related pathology
2022 · Hao Xiong, Fuzhou Hua, et al. · Frontiers in Aging Neuroscience · 26
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Roles of neuroligins in central nervous system development: focus on glial neuroligins and neuron neuroligins
2022 · Xing Liu, Fuzhou Hua, et al. · Journal of Translational Medicine · 48
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Dual roles of interleukin-33 in cognitive function by regulating central nervous system inflammation
2022 · Xiuqin Rao, Fuzhou Hua, et al. · Journal of Translational Medicine · 63
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Regulation of Mitophagy by Sirtuin Family Proteins: A Vital Role in Aging and Age-Related Diseases
2022 · Wei Wan, Fuzhou Hua, et al. · Frontiers in Aging Neuroscience · 74
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CB2R Activation Regulates TFEB-Mediated Autophagy and Affects Lipid Metabolism and Inflammation of Astrocytes in POCD
2022 · Lieliang Zhang, Xifeng Wang, et al. · Frontiers in Immunology · 46
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Long Non-coding RNAs and Circular RNAs: Insights Into Microglia and Astrocyte Mediated Neurological Diseases
2021 · Miaomiao Chen, Xingning Lai, et al. · Frontiers in Molecular Neuroscience · 96
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Astrocytes in Neural Circuits: Key Factors in Synaptic Regulation and Potential Targets for Neurodevelopmental Disorders
2021 · Xing Liu, Jun Ying, et al. · Frontiers in Molecular Neuroscience · 67
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Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism
2021 · Jialing Hu, Jiasheng Xu, et al. · Frontiers in Cell and Developmental Biology · 31
Relieving Cellular Energy Stress in Aging, Neurodegenerative, and Metabolic Diseases, SIRT1 as a Therapeutic and Promising Node
2021 · Yang Fang, Xifeng Wang, et al. · Frontiers in Aging Neuroscience · 50
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LncRNA 4344 promotes NLRP3-related neuroinflammation and cognitive impairment by targeting miR‐138-5p
2021 · Xiaojin Feng, Fenfang Zhan, et al. · Brain Behavior and Immunity · 70
The Mechanisms of Sevoflurane-Induced Neuroinflammation
2021 · Xiangfei Huang, Jun Ying, et al. · Frontiers in Aging Neuroscience · 59
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The Involvement of Lactosylceramide in Central Nervous System Inflammation Related to Neurodegenerative Disease
2021 · Wen Yu, Jun Ying, et al. · Frontiers in Aging Neuroscience · 26
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Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice
2021 · Lieliang Zhang, Fan Xiao, et al. · Frontiers in Pharmacology · 57
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Mitochondrial Dynamics: A Key Role in Neurodegeneration and a Potential Target for Neurodegenerative Disease
2021 · Danying Yang, Jun Ying, et al. · Frontiers in Neuroscience · 110
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MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats
2021 · Xiaojin Feng, Jialing Hu, et al. · Journal of Inflammation Research · 42
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Alpha-Lipoic Acid Preconditioning and Ischaemic Postconditioning Synergistically Protect Rats from Cerebral Injury Induced by Ischemia and Reperfusion Partly via Inhibition TLR4/MyD88/ NF-κB Signaling Pathway
2018 · Jing Zhang, Fan Xiao, et al. · Cellular Physiology and Biochemistry · 31
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