Epigenetic and Psychosocial Drivers of NeuroHIV in HIV+ South African Adolescents
Description: PUBLIC HEALTH RELEVANCE: There are a substantial number of perinatally HIV-infected children in South Africa who are at increased risk of neurobehavioral and neurophysiological abnormalities. Interventions for these children need to be informed by elucidating the biological and environmental determinants of such abnormalities. This study will examine the influence of DNA methylation (an epigenetic process) and important environmental and psychosocial factors on HIV neuropathogenesis, with the goal of developing treatment strategies and identifying potential biomarkers.
Funding type: research
Funder scheme: R21
Start date: 2016-06-01
End date: 2019-05-31
Investigator: JACQUELINE HOARE
Institution: UNIVERSITY OF CALIFORNIA LOS ANGELES
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Funded outputs count: 10
Funder award ID: R21MH107327
OpenAlex ID: G2263939360