Cellular senescence as a mediator of mitochondrial dysfunction-induced aging
Description: NARRATIVE Dysfunctional mitochondria are thought to be an underlying cause of many of the disorders associated with aging. This study will determine how the cellular damage response known as cellular senescence links mitochondrial dysfunction to aging, and will test whether interventions designed to prevent or eliminate senescent cells can prevent the phenotypes associated with aging.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2016-08-01
End date: 2021-04-30
Investigator: JUDITH CAMPISI
Institution: BUCK INSTITUTE FOR RESEARCH ON AGING
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 24
Funder award ID: R01AG051729
OpenAlex ID: G3428430834