The FERTILE Study: Evaluating ovarian toxicity Outcomes Following Immunotherapy in Triple-Negative Breast Cancer (TNBC)
Description: Immunotherapy causes substantial damage to ovaries in mice. It is not known if immunotherapy can cause similar damage to human ovaries, leading to infertility and early-onset menopause. This is a crucial information gap for patients. This study will assess ovarian function in premenopausal women with early-stage, curable triple negative breast cancer receiving chemoimmunotherapy, and will provide the first prospective human data on the impact of chemoimmunotherapy on ovarian function.
Funder: Medical Research Future Fund
Amount: A$652,500
Funding type: grant
Funder scheme: 2024 Infertility, Pregnancy Loss and Menopause
Start date: 2025-06-01
End date: 2028-09-30
Investigator: Wanyuan Cui
Institution: University of Melbourne
Funded outputs count: 0
Funder award ID: MRF2044521
OpenAlex ID: G6154367295