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F30DK120213

Funded outputs count: 11
Funder award ID: F30DK120213
OpenAlex ID: G6156566228
Modular pooled discovery of synthetic knockin sequences to program durable cell therapies
2023 · Franziska Blaeschke, Yan Yi Chen, et al. · Cell · 70
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
2022 · Brian R. Shy, Vivasvan S. Vykunta, et al. · Nature Biotechnology · 219
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Hybrid ssDNA repair templates enable high yield genome engineering in primary cells for disease modeling and cell therapy manufacturing
2021 · Brian R. Shy, Vivasvan Vykunta, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 17
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XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment
2021 · Youjin Lee, Derek Bogdanoff, et al. · Science Advances · 114
Genetic Disease and Therapy
2021 · Theodore L. Roth, Alexander Marson · Annual Review of Pathology Mechanisms of Disease · 62
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Editing of Endogenous Genes in Cellular Immunotherapies
2020 · Theodore L. Roth · Current Hematologic Malignancy Reports · 3
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
2020 · Theodore L. Roth, P. Jonathan Li, et al. · Cell · 186
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Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
2019 · David N. Nguyen, Theodore L. Roth, et al. · Nature Biotechnology · 312
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Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits
2019 · Theodore L. Roth, P. Jonathan Li, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 · Judd F. Hultquist, Joseph Hiatt, et al. · Nature Protocols · 126
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
2018 · Eric Shifrut, Julia Carnevale, et al. · Cell · 566
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