Award

Methods and software tool for complex trait analyses using multi-omics data

Description: This project aims to develop methods to disentangle the contribution of people’s difference in DNA sequence, DNA methylation, and gene expression to their difference in characteristics (including risks to diseases), and to utilise these information to predict disease risks of different people. This project also aims to develop a versatile and efficient computer software to implement the methods being proposed in this project, as well as all other commonly used methods in the research community.
Amount: A$574,000
Funding type: research
Funder scheme: Project Grants - Standard Project Grant
Start date: 2016-01-01
End date: 2019-12-31
Investigator: A/Pr Yang
Institution: University of Queensland
Funded outputs count: 36
Funder award ID: 1107258
OpenAlex ID: G6172650940
2022 · Ting Qi, Yang Wu, et al. · Nature Genetics · 253
2022 · Couvy-Duchesne, Baptiste, Bottani, Simona, et al. · HAL
2021 · Wenhan Chen, Yang Wu, et al. · Nature Communications · 66
2021 · Gibran Hemani, Joseph E. Powell, et al. · Nature · 28
2021 · Kathryn E. Kemper, Loic Yengo, et al. · Nature Communications · 42
2021 · Baptiste Couvy-Duchesne, Futao Zhang, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
2020 · Baptiste Couvy‐Duchesne, Lachlan T. Strike, et al. · Human Brain Mapping · 25
2020 · Costanza L. Vallerga, Futao Zhang, et al. · Nature Communications · 152
2019 · Longda Jiang, Zhili Zheng, et al. · Nature Genetics · 524
2019 · Abdel Abdellaoui, David Hugh-Jones, et al. · Nature Human Behaviour · 260
2019 · Qian Zhang, Costanza L. Vallerga, et al. · Genome Medicine · 485
2019 · Julia Sidorenko, Irfahan Kassam, et al. · Nature Communications · 82
2019 · Futao Zhang, Wenhan Chen, et al. · Genome biology · 165
2019 · Sally Mortlock, Restuadi Restuadi, et al. · Clinical Epigenetics · 44
2018 · Loic Yengo, Matthew R. Robinson, et al. · Nature Human Behaviour · 148
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