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Single cell characterization of the biomaterial immune and stromal response

Description: This proposal will use single cell analysis to evaluate immune cells that respond to different biomaterials that model tissue repair versus fibrosis. The results will provide new tools for identifying cells that may be present in many diseases. It will also increase our understanding of how the body responds to medical implants, differences between male and female responses, and new therapeutic targets to enhance tissue repair or reduce fibrosis.
Funding type: research
Funder scheme: R01
Start date: 2020-08-06
End date: 2025-04-30
Investigator: JENNIFER H ELISSEEFF
Institution: JOHNS HOPKINS UNIVERSITY
Funded outputs count: 7
Funder award ID: R01EB028796
OpenAlex ID: G581196085
2026 · Rindone, Alexandra, Nagaraj, Sushma, et al. · Zenodo (CERN European Organization for Nuclear Research)
2024 · Jin Han, Alexandra N. Rindone, et al. · Advanced Materials · 34
2021 · Erika M. Moore, David R. Maestas, et al. · Science Advances · 52
2021 · Jin Han, Christopher Cherry, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
2021 · Christopher Cherry, David R. Maestas, et al. · Nature Biomedical Engineering · 121
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