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R01 DK054388

Funded outputs count: 29
Funder award ID: R01 DK054388
OpenAlex ID: G618421067
Structure of putative tumor suppressor ALDH1L1
2022 · Yaroslav Tsybovsky, Valentin Sereda, et al. · Communications Biology · 12
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The Role of Single-Nucleotide Polymorphisms in the Function of Candidate Tumor Suppressor ALDH1L1
2019 · Sergey A. Krupenko, David A. Horita · Frontiers in Genetics · 26
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Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
2019 · Natalia I. Krupenko, Jaspreet Sharma, et al. · Scientific Reports · 29
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Loss of ALDH1L1 folate enzyme confers a selective metabolic advantage for tumor progression
2019 · Sergey A. Krupenko, Natalia I. Krupenko · Chemico-Biological Interactions · 51
Modeling of interactions between functional domains of ALDH1L1
2017 · David A. Horita, Sergey A. Krupenko · Chemico-Biological Interactions · 6
Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype
2017 · Zahra Ashkavand, Ciara O'Flanagan, et al. · Molecular Cancer Research · 41
Ceramide Synthase 6 Is a Novel Target of Methotrexate Mediating Its Antiproliferative Effect in a p53-Dependent Manner
2016 · Baharan Fekry, Amin Esmaeilniakooshkghazi, et al. · PLoS ONE · 52
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Aldehyde dehydrogenase homologous folate enzymes: Evolutionary switch between cytoplasmic and mitochondrial localization
2014 · Natalia I. Krupenko, Roger S. Holmes, et al. · Chemico-Biological Interactions · 16
Rho GTPases RhoA and Rac1 Mediate Effects of Dietary Folate on Metastatic Potential of A549 Cancer Cells through the Control of Cofilin Phosphorylation
2014 · Natalia V. Oleinik, Kristi L. Helke, et al. · Journal of Biological Chemistry · 50
JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1
2014 · A Prakasam, S Ghose, et al. · Cell Death and Disease · 28
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A Novel Tumor Suppressor Function of Glycine N-Methyltransferase Is Independent of Its Catalytic Activity but Requires Nuclear Localization
2013 · Suchandra DebRoy, Inga I. Kramarenko, et al. · PLoS ONE · 49
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Folate Stress Induces Apoptosis via p53-dependent de Novo Ceramide Synthesis and Up-regulation of Ceramide Synthase 6
2013 · L.Alexis Hoeferlin, Baharan Fekry, et al. · Journal of Biological Chemistry · 72
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The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1
2013 · Yaroslav Tsybovsky, Yuryi Malakhau, et al. · Chemico-Biological Interactions · 13
Molecular mechanisms underlying the potentially adverse effects of folate
2012 · Kyle C. Strickland, Natalia I. Krupenko, et al. · Clinical Chemistry and Laboratory Medicine (CCLM) · 71
Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress
2011 · L. A. Hoeferlin, N. V. Oleinik, et al. · Genes & Cancer · 59
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Conserved Catalytic Residues of the ALDH1L1 Aldehyde Dehydrogenase Domain Control Binding and Discharging of the Coenzyme
2011 · Yaroslav Tsybovsky, Sergey A. Krupenko · Journal of Biological Chemistry · 34
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Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase
2011 · Kyle C. Strickland, Natalia I. Krupenko, et al. · Chemico-Biological Interactions · 45
Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes
2011 · Kyle C. Strickland, Roger S. Holmes, et al. · Chemico-Biological Interactions · 21
ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A
2010 · N V Oleinik, N I Krupenko, et al. · Oncogene · 80
ALDH1L2 Is the Mitochondrial Homolog of 10-Formyltetrahydrofolate Dehydrogenase
2010 · Natalia I. Krupenko, Natalia I. Krupenko, et al. · Journal of Biological Chemistry · 114
Acyl Carrier Protein-specific 4′-Phosphopantetheinyl Transferase Activates 10-Formyltetrahydrofolate Dehydrogenase
2009 · Kyle C. Strickland, L.Alexis Hoeferlin, et al. · Journal of Biological Chemistry · 26
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Thyssenkrupp blues. I tempi morti. Conversazione con Pietro Balla e Monica Repetto
2009 · Edoardo Bruno, Bruno Roberti, et al. · Filmcritica · 1
FDH: An aldehyde dehydrogenase fusion enzyme in folate metabolism
2008 · Sergey A. Krupenko · Chemico-Biological Interactions · 98
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 · John D. Cahoy, Ben Emery, et al. · Journal of Neuroscience · 3,119
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Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase
2007 · C. Lee Elmore, Xuchu Wu, et al. · Molecular Genetics and Metabolism · 114
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