Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.
Description: Women are protected from cardiovascular disease as compared to age-matched men, an effect lost with age. Understanding protective factors that act in females could be used to treat hypertension, heart failure and stroke in males at all ages, and maintain protection in elderly women. Our studies aim to determine if relaxin, an ovarian hormone, can promote cardiovascular health in women.
Amount: A$1,049,000
Funding type: research
Funder scheme: Project Grants - Standard Project Grant
Start date: 2016-01-01
End date: 2019-12-31
Investigator: Kate Denton
Institution: Monash University
Funded outputs count: 9
Funder award ID: 1101552
OpenAlex ID: G6195427896