Impact of frailty and lifestyle-related diseases on the healthy life expectancy of Japanese community-dwelling older adults
Description: We conducted a 7 to 8-year prospective study to investigate the relationship between frailty, lifestyle-related diseases, and loss of independence leading to the onset of disability or death among Japanese community-dwelling older adults. Frailty was significantly associated with incident loss of independence, which showed approximately two-fold higher risk than non-frail participants. The population attributable fraction of loss of independence, which means the estimated contribution of each risk factor to the total events of loss of independence, was the greatest for prefrailty (19%), followed by frailty (12%). It was suggested that the prevention of frailty and pre-frailty could reduce the occurrence of loss of independence by up to 30% in 8 years. Our findings suggest that the screening and the intervention for frailty and lifestyle-related diseases in the early stages of old age might be beneficial in prolonging healthy life expectancy of Japanese community-dwelling older adults.
Amount: ¥16,380,000
Funding type: research
Funder scheme: Grant-in-Aid for Scientific Research (B)
Start date: 2017-04-01
End date: 2020-03-31
Investigator: Akihiko KITAMURA
Institution: Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Topic: Frailty in Older Adults
Subfield: Geriatrics and Gerontology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 20
Funder award ID: 17H04140
OpenAlex ID: G6202682242