Epigenetic Aging Biomarkers of Mild Cognitive Impairment, Alzheimer's Disease and Related Dementias, and Brain Aging
Description: This project will identify blood-based epigenetic aging biomarkers predicting risk of mild cognitive impairment (MCI), Alzheimer’s disease and related dementias (ADRD), and brain aging. These biomarkers can be used to identify older adults early in the ADRD disease course to potentially prevent irreversible cognitive and functional decline. The proposed research will support NIA’s public health mission by addressing the NIA 2020- 2025 Strategic Directions for Research goals of understanding how “molecular bases of changes associated with aging contribute to the development and course of age-related dementia” and identifying “biological and clinical markers for early detection of cognitive decline, MCI, and AD.”
Funder: National Institute on Aging
Funding type: research
Funder scheme: RF1
Start date: 2021-08-01
End date: 2024-07-31
Investigator: ALADDIN SHADYAB
Institution: UNIVERSITY OF CALIFORNIA, SAN DIEGO
Funded outputs count: 19
Funder award ID: RF1AG074345
OpenAlex ID: G1480889865