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ERA-NET Transcan - RISEBrain - Charakterisierung des immunsuppressiven Tumormikromilieus von Hirnmetastasen und dessen therapeutischer Modulation - Standort: Technische Universität Dresden

Amount: €180,000
Funding type: grant
Funder scheme: Volkskrankheiten
Start date: 2023-04-01
End date: 2026-03-31
Institution: Technische Universität Dresden
Funded outputs count: 10
Funder award ID: 01KT2304B
OpenAlex ID: G6261239226
Stemness overcomes IFNγ-induced antitumour exhaustion in human macrophages
2026 · Jessica Nitsche, Clara Jana-Lui Busch, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Patient-derived resources for decoding and targeting brain metastases ecosystems
2026 · Manuel Valiente, Lal Era Aydoğan, et al. · EMBO Molecular Medicine
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Intratumoral regulatory T cells are associated with treatment response to neoadjuvant chemotherapy and prognosis in gastroesophageal adenocarcinoma
2025 · Franziska Baenke, Antonia Stammberger, et al. · OncoImmunology · 1
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Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer
2025 · Rebecca Rothe, Antje Tunger, et al. · Frontiers in Immunology · 2
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2178TiP Fecal microbiota capsules from healthy donors to improve treatment response in patients with locally advanced, resectable gastric or gastro-esophageal junction adenocarcinoma: A randomized, placebo-controlled phase II study (CAPGO)
2025 · T. van den Ende, S. Siegerink, et al. · Annals of Oncology · 1
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RevCAR-mediated T-cell response against PD-L1-expressing cells turns suppression into activation
2025 · Eugenia Crespo, Liliana R. Loureiro, et al. · npj Precision Oncology · 8
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TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells
2024 · Neibla Priego, Ana de Pablos-Aragoneses, et al. · Cancer Discovery · 53
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Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients
2024 · Johanna Kirchner, Ioana Plesca, et al. · Frontiers in Immunology · 14
Tumor-targeted therapy with BRAF-inhibitor recruits activated dendritic cells to promote tumor immunity in melanoma
2024 · Florian Hornsteiner, Janine Vierthaler, et al. · Journal for ImmunoTherapy of Cancer · 9
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Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
2024 · Susann Winter, Katharina S. Götze, et al. · Leukemia · 41
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