The establishment of a biomimetic human iPSC-derived cornea-on-a-chip for the pre-clinical evaluation of ophthalmic nanomedicines
Description: This research envisions the establishment of a dynamic human cornea model through the interdisciplinary approach combining human induced pluripotent stem cells (iPSC) and microfluidics technologies. This platform will enable us to evaluate the pre-clinical efficacy and safety of the sophisticated ophthalmic nanoparticles that have the therapeutic potential in age-related eye diseases. Through that, we will be able to spatiotemporally evaluate the efficacy/toxicity and dynamic movement of nanomedicines.
Amount: ¥4,290,000
Funding type: fellowship
Funder scheme: Grant-in-Aid for Early-Career Scientists
Start date: 2020-04-01
End date: 2023-03-31
Investigator: Rodi ABDALKADER
Institution: Ritsumeikan University(2021-2022)Kyoto University(2020)
Funded outputs count: 6
Funder award ID: 20K20168
OpenAlex ID: G6423722968