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From brain maps to mechanisms: Modelling the pathophysiology of dementia

Description: As the brain ages, the relationship between its structure and function also changes. In this study, I will use detailed computational modelling and extensive analyses of brain dynamics to improve interventional strategies by: 1. Characterising healthy and unhealthy brain dynamics during ageing; 2. Classifying the various subtypes of pathological dynamics; and 3. Predicting pathological neurodegeneration by identifying the earliest signs of perturbations in healthy ageing.
Amount: A$604,500
Funding type: grant
Funder scheme: Targeted Calls for People - NHMRC-ARC Dementia Research Development Fellowship
Start date: 2016-01-01
End date: 2019-12-31
Investigator: Leonardo Gollo
Institution: Queensland Institute of Medical Research
Funded outputs count: 14
Funder award ID: 1110975
OpenAlex ID: G6428945935
2022 · Arianna Polverino, Emahnuel Troisi Lopez, et al. · medRxiv · 6
2021 · Pierpaolo Sorrentino, Rosaria Rucco, et al. · Scientific Reports · 82
2021 · James C. Pang, Leonardo L. Gollo, et al. · NeuroImage · 43
2019 · Pierpaolo Sorrentino, Rosaria Rucco, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6
2019 · Leonardo L. Gollo, Muhsin Karim, et al. · Frontiers in Neural Circuits · 2
2019 · James A. Roberts, Leonardo L. Gollo, et al. · Nature Communications · 264
2018 · Jennifer N. Kerkman, Andreas Daffertshofer, et al. · Science Advances · 165
2018 · Penelope Kale, Andrew Zalesky, et al. · Network Neuroscience · 38
2017 · Leonardo L. Gollo · Journal of The Royal Society Interface · 41
2017 · Luca Cocchi, Leonardo L. Gollo, et al. · Progress in Neurobiology · 515
2017 · Leonardo L. Gollo, James A. Roberts, et al. · NeuroImage · 146
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