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ERC-2014- AdG/669622

Funded outputs count: 27
Funder award ID: ERC-2014- AdG/669622
OpenAlex ID: G644691528
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2
2024 · Selim Chaib, José Alberto López-Domínguez, et al. · Nature Cancer · 114
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Mucosal TLR5 activation controls healthspan and longevity
2024 · Jae Sung Lim, Eun Jae Jeon, et al. · Nature Communications · 26
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Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype
2023 · Mate Maus, Vanessa López-Polo, et al. · Nature Metabolism · 213
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells
2023 · Domhnall McHugh, Bin Sun, et al. · Nature Cell Biology · 59
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Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair
2023 · Marta Kovatcheva, Elena Melendez, et al. · Nature Metabolism · 58
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Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice
2023 · Inés Domínguez‐López, Marta Kovatcheva, et al. · Journal of the Science of Food and Agriculture · 26
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Human senescent fibroblasts trigger progressive lung fibrosis in mice
2023 · Fernanda Hernandez-Gonzalez, Neus Prats, et al. · Aging · 37
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Targeting Mitochondria to Control Ageing and Senescence
2023 · Margherita Protasoni, Manuel Serrano · Pharmaceutics · 26
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Cellular senescence enhances adaptive anticancer immunosurveillance
2022 · Ines Marin, Manuel Serrano, et al. · OncoImmunology · 18
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The efficacy of chemotherapy is limited by intratumoural senescent cells that persist through the upregulation of PD-L2
2022 · Selim Chaib, José Alberto López-Domínguez, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 7
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Fatty acids homeostasis during fasting predicts protection from chemotherapy toxicity
2022 · Marta Barradas, Adrián Plaza, et al. · Nature Communications · 30
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The lysosomal proteome of senescent cells contributes to the senescence secretome
2022 · Miguel Rovira, Rebecca Sereda, et al. · Aging Cell · 125
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The trophectoderm acts as a niche for the inner cell mass through C/EBPα-regulated IL-6 signaling
2022 · Marcos Plana-Carmona, Gregoire Stik, et al. · Stem Cell Reports · 13
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Induction of senescence renders cancer cells highly immunogenic
2022 · Inés Marín, Olga Boix, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6
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Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
2022 · Ryan Wallis, Deborah Milligan, et al. · Aging · 58
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Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
2022 · Dafni Chondronasiou, Diljeet Gill, et al. · Aging Cell · 134
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A novel redox cycle diverts cells from oncogene-induced senescence into cancer
2021 · Mate Maus, Manuel Serrano · Molecular Cell · 3
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Restoration of energy homeostasis by SIRT6 extends healthy lifespan
2021 · A. Roichman, S. Elhanati, et al. · Nature Communications · 208
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MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation
2021 · Cristina Batlle, Isabel Calvo, et al. · Communications Biology · 21
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Dissection of two routes to naïve pluripotency using different kinase inhibitors
2021 · Ana Martinez-Val, Cian J. Lynch, et al. · Nature Communications · 28
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Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation
2021 · Jorge Blázquez-Prieto, Covadonga Huidobro, et al. · Translational research · 38
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Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells
2020 · Irène Aksoy, Cloé Rognard, et al. · Stem Cell Reports · 48
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Manipulating the Mediator complex to induce naïve pluripotency
2020 · Cian J. Lynch, Raquel Bernad, et al. · Experimental Cell Research · 7
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Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells
2020 · Timothy P. Cash, Sonia Alcalá, et al. · Cancers · 15
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Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
2020 · M. C. Wilkes, K. Siva, et al. · Nature Communications · 17
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