Role of arterial stiffness in the decline of cognitive control in aging
Description: Narrative Stiffening of the brain's arteries (arteriosclerosis) is thought to be a key factor in the development of Alzheimer's disease, which is important because in most cases arteriosclerosis can be prevented. Taking advantage of a new method that allows us to measure the health of the brain's arteries with unprecedented precision, we plan to study the overlap between problems with arterial stiffening, loss of brain tissue and connectivity, brain function and cognitive control (i.e., our ability to flexibly perform tasks and adjust to changing contextual demands). If successful, this research may help devise strategies for possible individualized, precision-medicine interventions to stave off early phases of age-related cognitive decline and dementia.
Funder: National Institute on Aging
Funding type: research
Funder scheme: RF1
Start date: 2019-04-15
End date: 2024-06-30
Investigator: MONICA FABIANI
Institution: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
Funded outputs count: 28
Funder award ID: RF1AG062666
OpenAlex ID: G4951996634