Regulatory Mechanisms in a Homeostatic Model of Geriatric Voiding Problems and Incontinence
Description: Urinary incontinence is a common and debilitating geriatric syndrome for which current therapies are frequently ineffective and associated with bothersome side effects and significant expense. A traditional view focused entirely on the bladder represents a barrier to the development of more effective, integrative treatments. I propose that a broader and more holistic homeostatic model of urinary control is more appropriate to a geriatric context. With this career development Award I propose to acquire very selected skills at the bench which will permit me to test a specific mechanism by which brain control influences bladder volume sensitivity, while I also gain the necessary skills and experience to become a thought-leader in the development of new understandings of, and therapies for, urinary dysfunction and symptom complexes in later life as a geriatric syndrome.
Funder: National Institute on Aging
Funding type: career_development
Funder scheme: K76
Start date: 2016-09-15
End date: 2022-05-31
Investigator: PHILLIP PAUL SMITH
Institution: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 13
Funder award ID: K76AG054777
OpenAlex ID: G3669245876