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22311
Funder:
Cancer Research UK
Funded outputs count:
168
Funder award ID:
22311
OpenAlex ID:
G6518970744
Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression
2021
·
Linda Julian
, Gregory Naylor
, et al.
·
eLife
·
16
PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer
2021
·
Laura C. A. Galbraith
, Ernest Mui
, et al.
·
Oncogene
·
69
PDF
E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
2021
·
Syed Feroj Ahmed
, Lori Buetow
, et al.
·
Oncogene
·
16
PDF
An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeleton
2021
·
Jana K. Schniete
, Peter W. Tinning
, et al.
·
Scientific Reports
·
4
PDF
A RAC-GEF network critical for early intestinal tumourigenesis
2021
·
K. A. Pickering
, K. Gilroy
, et al.
·
Nature Communications
·
27
PDF
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
2021
·
Arafath K. Najumudeen
, Fatih Ceteci
, et al.
·
Nature Genetics
·
290
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
2020
·
Timothy J. Humpton
, Koji Nomura
, et al.
·
Genes & Development
·
11
PDF
D-mannose suppresses macrophage IL-1β production
2020
·
Simone Torretta
, Alessandra Scagliola
, et al.
·
Nature Communications
·
226
PDF
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
2020
·
Mauro Corrado
, Joy Edwards-Hicks
, et al.
·
Cell Metabolism
·
69
PDF
18F-Fluciclovine PET metabolic imaging reveals prostate cancer tumour heterogeneity associated with disease resistance to androgen deprivation therapy
2020
·
Gaurav Malviya
, Rachana Patel
, et al.
·
EJNMMI Research
·
21
PDF
Developing a coordinate-based strategy to support cognitive targeted prostate biopsies and correlative spatial-histopathological outcome analysis
2020
·
Keiran D Clement
, Lizzy Day
, et al.
·
Asian Journal of Andrology
·
2
Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase
2020
·
Angela Maria Savino
, Sara Isabel Fernandes
, et al.
·
Nature Cancer
·
68
PDF
The conversion of formate into purines stimulates mTORC1 leading to CAD-dependent activation of pyrimidine synthesis
2020
·
Jacqueline Tait-Mulder
, Kelly Hodge
, et al.
·
Cancer & Metabolism
·
11
PDF
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
2020
·
Chatrin Chatrin
, Mads Gabrielsen
, et al.
·
Science Advances
·
97
PDF
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition
2020
·
Alba Roca-Portoles
, Giovanny Rodriguez-Blanco
, et al.
·
Cell Death and Disease
·
101
PDF
The RAC1 Target NCKAP1 Plays a Crucial Role in the Progression of Braf;Pten-Driven Melanoma in Mice
2020
·
Karthic Swaminathan
, Andrew Campbell
, et al.
·
Journal of Investigative Dermatology
·
17
Impact of Formate Supplementation on Body Weight and Plasma Amino Acids
2020
·
Sandeep Dhayade
, Matthias Pietzke
, et al.
·
Nutrients
·
9
Selection of established tumour cells through narrow diameter micropores enriches for elevated Ras/Raf/MEK/ERK MAPK signalling and enhanced tumour growth
2020
·
Dominika a Rudzka
, Susan Mason
, et al.
·
Small GTPases
·
7
Amino acid dependent formaldehyde metabolism in mammals
2020
·
Matthias Pietzke
, Guillermo Burgos-Barragan
, et al.
·
Communications Chemistry
·
31
PDF
Editorial: Perspectives in Small Animal Radionuclide Imaging
2020
·
Francesco Cicone
, Gaurav Malviya
, et al.
·
Frontiers in Medicine
·
2
PDF
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
2020
·
Arnaud Blomme
, Catriona A. Ford
, et al.
·
Nature Communications
·
182
PDF
Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma
2020
·
Nathiya Muthalagu
, Tiziana Monteverde
, et al.
·
Cancer Discovery
·
182
AAV Gene Therapy Prevents and Reverses Heart Failure in a Murine Knockout Model of Barth Syndrome
2020
·
Suya Wang
, Yifei Li
, et al.
·
Circulation Research
·
126
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome
2020
·
Nicholas Rooney
, Susan M. Mason
, et al.
·
Cancer Research
·
46
PDF
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
2020
·
Justine Bellier
, Marie-Julie Nokin
, et al.
·
Cell Reports
·
38
PDF
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