Effect of longevity genomes on the GH/IGF-1 phenotype and disease-free survival
Description: PUBLIC HEALTH RELEVANCE: Aging is a major risk factor for many diseases, including cardiovascular disease, cancer, diabetes, and dementia, which are among the leading causes of death in the elderly in the United States. Genetic constitution has a considerable impact on aging; thus, we use families of centenarians to identify protective genetic factors regulating hormonal and metabolic systems that allow people to remain healthy as they age and eventually reach exceptional longevity. Identification of factors that protect against age-related diseases is an important step in the development of interventions for prevention of aging and disease.
Funder: National Institute on Aging
Funding type: career_development
Funder scheme: K23
Start date: 2015-08-01
End date: 2022-04-30
Investigator: SOFIYA MILMAN
Institution: ALBERT EINSTEIN COLLEGE OF MEDICINE
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Funded outputs count: 25
Funder award ID: K23AG051148
OpenAlex ID: G8453291127