DNA origami nanostructures for iPSC generation and cell reprogramming
Description: Induced pluripotent stem cells (iPSCs) are critical for tissue replacement therapy, studying diseases, and trialling drugs. However, generating these cells and 'reprogramming' them, is expensive and time consuming, and produces cells of mixed quality. Making these cells requires the delivery of genes, which is not well understood. This research will develop new tools using 'DNA origami' to understand and improve how genes are delivered into cells, for safe and efficient generation of iPSCs.
Amount: A$688,400
Funding type: research
Funder scheme: Investigator Grants - Emerging Leadership 1 (EL1)
Start date: 2026-01-01
End date: 2030-12-31
Investigator: Jessica Kretzmann
Institution: University of Western Australia
Funded outputs count: 0
Funder award ID: 2041400
OpenAlex ID: G6561461434