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11650
Funder:
Cancer Research UK
Funded outputs count:
100
Funder award ID:
11650
OpenAlex ID:
G6591838237
Nilotinib in KIT-driven advanced melanoma: Results from the phase II single-arm NICAM trial
2024
·
James Larkin
, Richard Marais
, et al.
·
Cell Reports Medicine
·
20
PDF
Characterization of Tumor Responses in Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib in the Phase 3 Randomized Trial: REFLECT
2024
·
Richard S. Finn
, Shukui Qin
, et al.
·
Liver Cancer
·
9
Impact of the COVID-19 pandemic on patients with hepatocellular carcinoma in the West of Scotland: a cohort study
2023
·
Alistair Stewart McLaren
, Johannes A Spoor
, et al.
·
BMJ Open Gastroenterology
·
2
PDF
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance
2023
·
Christina Yap
, Jan Rekowski
, et al.
·
BMJ
·
29
PDF
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance
2023
·
Christina Yap
, Olga Solovyeva
, et al.
·
BMJ
·
52
PDF
Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study
2023
·
Olga Solovyeva
, Munyaradzi Dimairo
, et al.
·
BMC Medicine
·
13
PDF
Tebentafusp in combination with durvalumab and/or tremelimumab in patients with metastatic cutaneous melanoma: a phase 1 study
2023
·
Omid Hamid
, Jessica C Hassel
, et al.
·
Journal for ImmunoTherapy of Cancer
·
33
PDF
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer
2023
·
Rebecca Kristeleit
, Ruth Plummer
, et al.
·
British Journal of Cancer
·
40
PDF
Olaparib and durvalumab in patients with relapsed small cell lung cancer (MEDIOLA): An open-label, multicenter, phase 1/2, basket study
2023
·
Matthew G. Krebs
, Jean-Pierre Delord
, et al.
·
Lung Cancer
·
42
PDF
SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol
2023
·
Aude Espinasse
, Olga Solovyeva
, et al.
·
BMJ Open
·
24
PDF
Liquid Biopsy for Pancreatic Cancer Detection Using Infrared Spectroscopy
2022
·
Alexandra Sala
, James M. Cameron
, et al.
·
Cancers
·
34
PDF
Lenvatinib dose, efficacy, and safety in the treatment of multiple malignancies
2022
·
Robert J. Motzer
, Matthew H. Taylor
, et al.
·
Expert Review of Anticancer Therapy
·
65
Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK Inhibitors
2022
·
Claire Glen
, Yun Yi Tan
, et al.
·
JACC CardioOncology
·
75
PDF
The need for reporting guidelines for early phase dose-finding trials: Dose-Finding CONSORT Extension
2022
·
Christina Yap
, Alun Bedding
, et al.
·
Nature Medicine
·
32
Upregulation of C/EBPα Inhibits Suppressive Activity of Myeloid Cells and Potentiates Antitumor Response in Mice and Patients with Cancer
2021
·
Ayumi Hashimoto
, Debashis Sarker
, et al.
·
Clinical Cancer Research
·
97
Pharmacodynamic Biomarkers Predictive of Survival Benefit with Lenvatinib in Unresectable Hepatocellular Carcinoma: From the Phase III REFLECT Study
2021
·
Richard S. Finn
, Masatoshi Kudo
, et al.
·
Clinical Cancer Research
·
79
PDF
Quantitative Multiplex Immunofluorescence Evaluation of the Tumor Microenvironment in Pretreatment Tumors of Patients with Metastatic Breast Cancer and Serous Ovarian Carcinoma Treated with Liposomal Eribulin
2021
·
Douglas K. Marks
, John Kucharczyk
, et al.
·
Cancer Investigation
Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours
2021
·
Mark R. Middleton
, Emma Dean
, et al.
·
British Journal of Cancer
·
126
PDF
Analyses of PD-L1 and Inflammatory Gene Expression Association with Efficacy of Nivolumab ± Ipilimumab in Gastric Cancer/Gastroesophageal Junction Cancer
2021
·
Ming Lei
, Nathan O. Siemers
, et al.
·
Clinical Cancer Research
·
90
PDF
A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection
2021
·
Valerio F. Annese
, Samadhan B. Patil
, et al.
·
Microsystems & Nanoengineering
·
35
PDF
Effects of Subsequent Systemic Anticancer Medication Following First-Line Lenvatinib: A Post Hoc Responder Analysis from the Phase 3 REFLECT Study in Unresectable Hepatocellular Carcinoma
2019
·
Angel Alsina
, Masatoshi Kudo
, et al.
·
Liver Cancer
·
76
PDF
Phase II randomised discontinuation trial of brivanib in patients with advanced solid tumours
2019
·
Robin L. Jones
, Mark J. Ratain
, et al.
·
European Journal of Cancer
·
29
PDF
Safety and Efficacy of Nivolumab Monotherapy in Recurrent or Metastatic Cervical, Vaginal, or Vulvar Carcinoma: Results From the Phase I/II CheckMate 358 Trial
2019
·
R. Wendel Naumann
, Antoine Hollebecque
, et al.
·
Journal of Clinical Oncology
·
440
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
2019
·
Claire S Reader
, Sabari Vallath
, et al.
·
The Journal of Pathology
·
115
PDF
Urine protein:creatinine ratio vs 24-hour urine protein for proteinuria management: analysis from the phase 3 REFLECT study of lenvatinib vs sorafenib in hepatocellular carcinoma
2019
·
Thomas R. Jeffry Evans
, Masatoshi Kudo
, et al.
·
British Journal of Cancer
·
28
PDF
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