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Research Center for Pharmacology and Drug Toxicology

Funding type: program
Funder scheme: P50
Start date: 1977-12-01
End date: 2011-09-29
Investigator: II ROBERTS
Institution: VANDERBILT UNIVERSITY
Funded outputs count: 188
Funder award ID: P50GM015431
OpenAlex ID: G2440397094
DP1 Activation Reverses Age-Related Hypertension Via NEDD4L-Mediated T-Bet Degradation in T Cells
2020 · Deping Kong, Qiangyou Wan, et al. · Circulation · 42
Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site
2019 · Shu Xu, Md. Jashim Uddin, et al. · Journal of Biological Chemistry · 25
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Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
2018 · Christi T Salisbury-Ruf, Clinton C Bertram, et al. · eLife · 25
Acetaminophen as a Renoprotective Adjunctive Treatment in Patients With Severe and Moderately Severe Falciparum Malaria: A Randomized, Controlled, Open-Label Trial
2018 · Katherine Plewes, Hugh W F Kingston, et al. · Clinical Infectious Diseases · 65
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Oxidation of C18 Hydroxy‐Polyunsaturated Fatty Acids to Epoxide or Ketone by Catalase‐Related Hemoproteins Activated with Iodosylbenzene
2017 · Tarvi Teder, William E. Boeglin, et al. · Lipids · 7
Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6
2017 · Antje Brüser, Anne Zimmermann, et al. · Scientific Reports · 39
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Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study
2017 · Katherine Plewes, Hugh W.F. Kingston, et al. · BMC Infectious Diseases · 91
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Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons
2017 · Lawrence R. Curtis, Claudia F. Bravo, et al. · Ecotoxicology and Environmental Safety · 20
A fungal catalase reacts selectively with the 13S fatty acid hydroperoxide products of the adjacent lipoxygenase gene and exhibits 13S-hydroperoxide-dependent peroxidase activity
2017 · Tarvi Teder, William E. Boeglin, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 16
Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1
2017 · Deping Kong, Juanjuan Li, et al. · Journal of Pharmacology and Experimental Therapeutics · 25
The Thr–His Connection on the Distal Heme of Catalase‐Related Hemoproteins: A Hallmark of Reaction with Fatty Acid Hydroperoxides
2016 · Zahra Mashhadi, Marcia E. Newcomer, et al. · ChemBioChem · 15
PKA regulatory IIα subunit is essential for PGD2-mediated resolution of inflammation
2016 · Deping Kong, Yujun Shen, et al. · The Journal of Experimental Medicine · 81
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Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
2016 · Olivier Boutaud, I. Romina Sosa, et al. · Cancer Prevention Research · 54
Cyclooxygenase-2 inhibition reduces stress-induced affective pathology
2016 · Joyonna Carrie Gamble-George, Rita Baldi, et al. · eLife · 55
The discovery and early structural studies of arachidonic acid
2016 · Sarah A. Martin, Alan R. Brash, et al. · Journal of Lipid Research · 145
Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain
2016 · Aurelia Vergeade, Clinton C. Bertram, et al. · Mitochondrion · 31
Assay of Endocannabinoid Oxidation by Cyclooxygenase-2
2016 · Shalley N. Kudalkar, Philip J. Kingsley, et al. · Methods in molecular biology · 9
Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension
2015 · Jing Wu, Kim Ramil C. Montaniel, et al. · Hypertension · 100
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Immune activation caused by vascular oxidation promotes fibrosis and hypertension
2015 · Jing Wu, Mohamed A. Saleh, et al. · Journal of Clinical Investigation · 237
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Competition and allostery govern substrate selectivity of cyclooxygenase-2
2015 · Michelle M. Mitchener, Daniel J. Hermanson, et al. · Proceedings of the National Academy of Sciences · 32
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Robust inhibitory effects of conjugated linolenic acids on a cyclooxygenase-related linoleate 10S-dioxygenase: Comparison with COX-1 and COX-2
2015 · Zahra Mashhadi, William E. Boeglin, et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 9
Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II–Induced Hypertension
2015 · Liang Xiao, Annet Kirabo, et al. · Circulation Research · 233
Action at a Distance
2015 · Anna L. Blobaum, Shu Xu, et al. · Journal of Biological Chemistry · 48
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Perioperative Intravenous Acetaminophen Attenuates Lipid Peroxidation in Adults Undergoing Cardiopulmonary Bypass: A Randomized Clinical Trial
2015 · Frederic T. Billings IV, Michael R. Petracek, et al. · PLoS ONE · 32
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Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
2015 · Mohamed A. Saleh, William G. McMaster, et al. · Journal of Clinical Investigation · 152
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