Mesenchymal stem cell senescence in diabetic nephropathy
Description: PUBLIC HEALTH RELEVANCE: Diabetic kidney disease is the most common cause of kidney failure in the United States and has no adequate cure. Stem cell transplantation is an exciting new treatment, with a potential to slow progression of kidney failure by injecting healthy stem cells to repair the kidney. However, if diabetes impairs their function, stem cells might be less effective. In this proposal, we will examine the feasibility of restoring the health of stem cells o that patients with diabetes might be able to benefit from participating in future stem cell transplant clinical trials for kidney disease.
Funding type: career_development
Funder scheme: K23
Start date: 2016-07-01
End date: 2022-12-31
Investigator: LATONYA J HICKSON
Institution: MAYO CLINIC JACKSONVILLE
Funded outputs count: 51
Funder award ID: K23DK109134
OpenAlex ID: G5999952138