Molecular Networks Underlying Resilience to Alzheimer's Disease Among APOE E4 Carriers
Description: PROJECT NARRATIVE Individuals with the ApoE e4 genotype have a substantially increased risk of developing Alzheimer's disease. The goal of this project is identify underlying biological interactions and networks that explain why some e4 carriers do not develop Alzheimer's disease, despite being high-risk. This research has the potential to uncover novel targets that can lead to the development of effective therapies for the prevention and treatment of Alzheimer's disease.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2017-09-30
End date: 2024-05-31
Investigator: CHRISTOPHER A. GAITERI
Institution: YALE UNIVERSITY
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Funded outputs count: 21
Funder award ID: R01AG057912
OpenAlex ID: G8948930875