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Whole-brain modeling of neurovascular pathways to neurodegeneration

Description: <b id="docs-internal-guid-0090d020-7fff-fb57-e5d4-fce12269bcfb">Can problems with blood flow in the brain help explain how Alzheimer’s disease and other dementias develop, and can we use brain imaging and modeling to better detect and understand this link?</b>

Funder: Alzheimer's Association

Funding type: research

Funder scheme: AARG-D

Start date: 2025-01-01

Investigator: Enzo Tagliazucchi

Institution: Adolfo Ibáñez University (Universidad Adolfo Ibáñez)

Funded outputs count: 4

Funder award ID: AARG-25-1490306

OpenAlex ID: G6807651601

Auditory brainstem response latencies, but not amplitudes, are associated with gray matter volumes across the human auditory pathway in older adults

2026 · Simón San-Martín, Cristian Aedo, et al. · bioRxiv (Cold Spring Harbor Laboratory)

White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β 2 ‐adrenergic receptor expression

2026 · Victor Vidal, Gonzalo Farías, et al. · Alzheimer s & Dementia

Mapping the neurovascular landscape in aging and dementia: cerebral small vessel disease markers in a multicenter Latin American cohort

2026 · Florencia Altschuler, Ana Maria Castro‐Laguardia, et al. · Alzheimer s & Dementia

Association of Fractional Anisotropy in White Matter Bundles with Plasma Biomarkers of Neurodegeneration and Glial Reactivity in Individuals with Cognitive Complaints without dementia

2026 · Patricio F. Riquelme, Isaias Mery, et al. · Research Square