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GRK1739/2
Funder:
Deutsche Forschungsgemeinschaft
Funded outputs count:
31
Funder award ID:
GRK1739/2
OpenAlex ID:
G6811514512
Homologous Recombination and Alternative End-Joining Repair Pathways are Important Determinants of Radiosensitivity to Proton Radiation Therapy
2026
·
Razan Hessenow
, Johann Matschke
, et al.
·
International Journal of Radiation Oncology*Biology*Physics
·
2
Berzosertib enhances sensitivity of pediatric diffuse midline glioma H3K27 altered cells to radiotherapy
2025
·
N Gorainow
, F Sander
, et al.
·
Klinische Pädiatrie
PDF
α-Ketoglutarate supplementation and NAD+ modulation enhance metabolic rewiring and radiosensitization in SLC25A1 inhibited cancer cells
2024
·
Kexu Xiang
, Mikhail Kunin
, et al.
·
Cell Death Discovery
·
18
PDF
Combined radiation- and immune checkpoint-inhibitor-induced pneumonitis – The challenge to predict and detect overlapping immune-related adverse effects from evolving laboratory biomarkers and clinical imaging
2023
·
Nika Guberina
, Florian Wirsdörfer
, et al.
·
Neoplasia
·
18
Accumulation of oncometabolite D-2-Hydroxyglutarate by SLC25A1 inhibition: A metabolic strategy for induction of HR-ness and radiosensitivity
2022
·
Kexu Xiang
, Christian Kalthoff
, et al.
·
Cell Death and Disease
·
17
PDF
Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation
2022
·
Isabell Goetting
, Safa Larafa
, et al.
·
Frontiers in Oncology
·
3
Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma Cells
2022
·
Alina Wittka
, Julia Ketteler
, et al.
·
Frontiers in Oncology
·
9
PDF
Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown
2021
·
Adam Krysztofiak
, Klaudia Szymonowicz
, et al.
·
iScience
·
29
PDF
Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy
2021
·
Violetta Ritter
, Franziska Krautter
, et al.
·
Cell Death and Disease
·
58
PDF
Metformin Protects against Radiation-Induced Acute Effects by Limiting Senescence of Bronchial-Epithelial Cells
2021
·
Christine Hansel
, Samantha Barr
, et al.
·
International Journal of Molecular Sciences
·
33
PDF
A New Twist in Protein Kinase B/Akt Signaling: Role of Altered Cancer Cell Metabolism in Akt-Mediated Therapy Resistance
2020
·
Isabell Götting
, Verena Jendrossek
, et al.
·
International Journal of Molecular Sciences
·
36
PDF
Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity
2020
·
Alina V. Meyer
, Diana Klein
, et al.
·
Frontiers in Oncology
·
7
PDF
The vascular nature of lung-resident mesenchymal stem cells
2020
·
Jennifer Steens
, Lea Klar
, et al.
·
Stem Cells Translational Medicine
·
43
PDF
Oncometabolites and the response to radiotherapy
2020
·
Kexu Xiang
, Verena Jendrossek
, et al.
·
Radiation Oncology
·
29
PDF
Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells
2020
·
Christine Hansel
, Verena Jendrossek
, et al.
·
International Journal of Molecular Sciences
·
85
PDF
Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactions
2020
·
Julia Ketteler
, Alina Wittka
, et al.
·
Cell Death and Disease
·
49
PDF
Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining
2020
·
Klaudia Szymonowicz
, Adam Krysztofiak
, et al.
·
Cells
·
54
PDF
Targeting ARID1A-mutant colorectal cancer: depletion of ARID1B increases radiosensitivity and modulates DNA damage response
2019
·
B. Niedermaier
, A. Sak
, et al.
·
Scientific Reports
·
36
PDF
The CD73/Ado System—A New Player in RT Induced Adverse Late Effects
2019
·
Simone de Leve
, Florian Wirsdörfer
, et al.
·
Cancers
·
26
PDF
Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research
2019
·
Nicole Dünker
, Verena Jendrossek
·
Cancers
·
46
PDF
Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors
2019
·
Alizée Steer
, Nils Cordes
, et al.
·
Frontiers in Molecular Biosciences
·
50
PDF
Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy
2019
·
Simone de Leve
, Florian Wirsdörfer
, et al.
·
Frontiers in Immunology
·
92
PDF
Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1
2019
·
Julia Ketteler
, Andrej Panic
, et al.
·
Journal of Clinical Medicine
·
31
PDF
High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation
2019
·
Sebastian Oeck
, Nathalie M. Malewicz
, et al.
·
Scientific Reports
·
12
PDF
Combining Radiotherapy and Immunotherapy in Lung Cancer: Can We Expect Limitations Due to Altered Normal Tissue Toxicity?
2018
·
Florian Wirsdörfer
, Simone De Leve
, et al.
·
International Journal of Molecular Sciences
·
131
PDF
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