Combatting mitochondrial DNA mutations using microbe-host signalling
Description: Mitochondria are powerhouses of the cell. Their assembly and function are encoded by a small mitochondrial genome. Mutations in the mitochondrial genome can cause devastating metabolic disorders and have been linked to many common age-related diseases. This project will reveal how specific bacteria in our environment can beneficially decrease the abundance of these mutations in our body, thus revealing a new mechanism that can be exploited to combat mitochondria-associated disease.
Amount: A$1,071,000
Funding type: research
Funder scheme: Ideas Grants - Ideas Grants
Start date: 2026-01-01
End date: 2029-12-31
Investigator: Steven Zuryn
Institution: The University of Queensland
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 1
Funder award ID: 2048665
OpenAlex ID: G6887116256