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PsiAlc - Präklinische Phase-II-Tests von Psilocybin bei Alkoholsucht

Amount: €289,800
Funding type: grant
Funder scheme: Volkskrankheiten
Start date: 2019-05-01
End date: 2023-06-30
Institution: Zentralinstitut für Seelische Gesundheit
Funded outputs count: 20
Funder award ID: 01EW1908
OpenAlex ID: G689263947
Epigenome-wide association study of psilocybin-induced methylome changes in alcohol use disorder
2026 · Marvin M. Urban, Lea Zillich, et al. · Translational Psychiatry · 1
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Visual Hallucinations in Serotonergic Psychedelics and Lewy Body Diseases
2025 · Nathan H Heller, Frederick Streeter Barrett, et al.
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Prefrontal electrophysiological biomarkers and mechanism-based drug effects in a rat model of alcohol addiction
2024 · Bettina Habelt, Dzmitry Afanasenkau, et al. · Translational Psychiatry · 6
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Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder
2024 · Lea Zillich, Metin Cetin, et al. · Alcoholism Clinical and Experimental Research · 13
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Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats
2023 · Jonathan R. Reinwald, Christian N. Schmitz, et al. · Translational Psychiatry · 25
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The ego in psychedelic drug action – ego defenses, ego boundaries, and the therapeutic role of regression
2023 · Tobias Buchborn, Hannes S. Kettner, et al. · Frontiers in Neuroscience · 27
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A shea butter-based ketamine ointment: The antidepressant effects of transdermal ketamine in rats
2023 · Merve Akan, Ivan Skorodumov, et al. · Behavioural Brain Research · 8
Mini-review: The neurobiology of treating substance use disorders with classical psychedelics
2023 · Marvin M. Urban, Moritz R. Stingl, et al. · Frontiers in Neuroscience · 45
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Psychedelic Targeting of Metabotropic Glutamate Receptor 2 and Its Implications for the Treatment of Alcoholism
2023 · Kevin Domanegg, Wolfgang H. Sommer, et al. · Cells · 22
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DNA methylation in cocaine use disorder–An epigenome-wide approach in the human prefrontal cortex
2023 · Eric Poisel, Lea Zillich, et al. · Frontiers in Psychiatry · 25
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mGlu2 mechanism-based interventions to treat alcohol relapse
2022 · Valentina Vengeliene, Rainer Spanagel · Frontiers in Pharmacology · 14
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Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum
2022 · Lea Zillich, Eric Poisel, et al. · Translational Psychiatry · 39
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Ten Points to Improve Reproducibility and Translation of Animal Research
2022 · Rainer Spanagel · Frontiers in Behavioral Neuroscience · 68
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Epigenetic Signatures of Smoking in Five Brain Regions
2022 · Lea Zillich, Eric Poisel, et al. · Journal of Personalized Medicine · 12
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Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism
2021 · Marcus W. Meinhardt, Simone Pfarr, et al. · Science Advances · 89
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Epigenome-wide association study of alcohol use disorder in five brain regions
2021 · Lea Zillich, Josef Frank, et al. · Neuropsychopharmacology · 36
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A common molecular mechanism for cognitive deficits and craving in alcoholism
2020 · Marcus W. Meinhardt, Simone Pfarr, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse
2020 · Marcus W. Meinhardt, Cansu Güngör, et al. · Neuropsychopharmacology · 65
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Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles: a longitudinal clinical study
2020 · Stephanie H. Witt, Josef Frank, et al. · Addiction · 35
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Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene
2019 · Jerome Clifford Foo, Valentina Vengeliene, et al. · Frontiers in Pharmacology · 17
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