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Monoamine oxidases as molecular players of cardiac senescence and failure

Amount: €256,200
Funding type: grant
Funder scheme: Biomedicina
Investigator: Claudia Binda
Institution: Università degli Studi di Pavia
Funded outputs count: 10
Funder award ID: 2014-0672
OpenAlex ID: G6911319818
Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures
2022 · Fredrik Ekström, Andrea Gottinger, et al. · ACS Medicinal Chemistry Letters · 36
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Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging
2020 · Luca Giacinto Iacovino, Nicola Manzella, et al. · ACS Chemical Biology · 19
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Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B
2020 · Damijan Knez, Natalia Colettis, et al. · Journal of Medicinal Chemistry · 53
Rôles du stress oxydant et de ses dérivés dans les mécanismes physiopathologiques de l’insuffisance cardiaque
2019 · Yohan Santin · Thèses en ligne de l'Université Toulouse III (Université Toulouse III)
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Roles of oxidative stress and its derivatives in the pathophysiological mechanisms of heart failure
2019 · Santin, Yohan · theses.fr (ABES)
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The structure of monoamine oxidases: past, present, and future
2018 · Luca Giacinto Iacovino, Francesca Magnani, et al. · Journal of Neural Transmission · 72
Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy
2018 · Nicola Manzella, Yohan Santin, et al. · Aging Cell · 106
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Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis
2018 · Joana Reis, Nicola Manzella, et al. · Journal of Medicinal Chemistry · 95
Oleuropein Aglycone Protects against MAO‐A‐Induced Autophagy Impairment and Cardiomyocyte Death through Activation of TFEB
2018 · Caterina Miceli, Yohan Santin, et al. · Oxidative Medicine and Cellular Longevity · 55
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Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing
2017 · Damien Maggiorani, Nicola Manzella, et al. · Oxidative Medicine and Cellular Longevity · 114
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