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32171288
Funder:
National Natural Science Foundation of China
Funded outputs count:
14
Funder award ID:
32171288
OpenAlex ID:
G6931955636
Human c GAS Drives LINE ‐1 Transcriptional Activation to Trigger MAVS ‐Dependent Cellular Senescence
2026
·
Zhixi Chen
, Lingjiang Chen
, et al.
·
Aging Cell
·
3
PIPKIγ promotes non-homologous end joining through LIG4 to enhance radiotherapy resistance in triple-negative breast cancer
2025
·
Wenge Dong
, Haiping Zhang
, et al.
·
Cell Death and Disease
PDF
Sirt2 ablation exacerbates Sod1 knockout-induced progeroid phenotype in mice
2025
·
Anke Geng
, Xiaona Wang
, et al.
·
Redox Biology
·
6
Lycorine hydrochloride directly targets UBA1 to suppress cellular senescence
2025
·
Jiaqing Yang
, Junhao Xu
, et al.
·
Acta Pharmaceutica Sinica B
·
1
PDF
The transcription factor PAX5 activates human LINE1 retrotransposons to induce cellular senescence
2024
·
Huanyin Tang
, Jiaqing Yang
, et al.
·
EMBO Reports
·
20
PDF
The cGAS-Ku80 complex regulates the balance between two end joining subpathways
2024
·
Haiping Zhang
, Lijun Jiang
, et al.
·
Cell Death and Differentiation
·
13
PDF
SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner
2024
·
Anke Geng
, Jiahui Sun
, et al.
·
Nucleic Acids Research
·
24
PDF
Nuclear cGAS restricts L1 retrotransposition by promoting TRIM41-mediated ORF2p ubiquitination and degradation
2023
·
Zhengyi Zhen
, Yu Chen
, et al.
·
Nature Communications
·
48
PDF
Impaired end joining induces cardiac atrophy in a Hutchinson–Gilford progeria mouse model
2023
·
Yu Chen
, Shiqi Huang
, et al.
·
Proceedings of the National Academy of Sciences
·
13
Androgen signaling stabilizes genomes to counteract senescence by promoting XRCC4 transcription
2023
·
Yu Chen
, Zhengyi Zhen
, et al.
·
EMBO Reports
·
13
PDF
Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer
2023
·
Weina Zhang
, Mingzhu Wang
, et al.
·
Nature Communications
·
28
PDF
Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer
2023
·
Xiaoxiang Sun
, Huanyin Tang
, et al.
·
Nature Cancer
·
66
Chrysin impairs genomic stability by suppressing DNA double-strand break repair in breast cancer cells
2022
·
Anke Geng
, Shiya Xu
, et al.
·
Cell Cycle
·
20
PDF
Determinantes de la criminalidad: análisis de los resultados.(Primera Parte) (Segunda Parte) (Tercera Parte)
2007
·
Paulina Ruiz Cabello
, Macarena Cea Martínez
, et al.
·
Dialnet (Universidad de la Rioja)
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