Award

Biochemical Nature and Significance of Skin Autofluorescence in Diabetes

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Funding type: research

Funder scheme: R21

Start date: 2007-08-01

End date: 2010-07-31

Investigator: DAVID RAYMOND SELL

Institution: CASE WESTERN RESERVE UNIVERSITY

Funded outputs count: 14

Funder award ID: R21DK079432

OpenAlex ID: G5167760166

Evidence of glucuronidation of the glycation product LW-1: tentative structure and implications for the long-term complications of diabetes

2018 · David R. Sell, Ina Nemet, et al. · Glycoconjugate Journal · 10

The pecking order of skin Advanced Glycation Endproducts (AGEs) as long-term markers of glycemic damage and risk factors for micro- and subclinical macrovascular disease progression in Type 1 diabetes

2016 · Vincent M. Monnier, Saul Genuth, et al. · Glycoconjugate Journal · 38

New Locus for Skin Intrinsic Fluorescence in Type 1 Diabetes Also Associated With Blood and Skin Glycated Proteins

2016 · Delnaz Roshandel, Ronald Klein, et al. · Diabetes · 28

Skin collagen fluorophore LW-1 versus skin fluorescence as markers for the long-term progression of subclinical macrovascular disease in type 1 diabetes

2016 · David R. Sell, Wanjie Sun, et al. · Cardiovascular Diabetology · 24

Skin collagen advanced glycation endproducts (AGEs) and the long-term progression of sub-clinical cardiovascular disease in type 1 diabetes

2015 · Vincent M Monnier, Wanjie Sun, et al. · Cardiovascular Diabetology · 65

Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

2015 · P. Gopal, H.R. Gosker, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 20

Advanced Glycation End-Products Reduce Collagen Molecular Sliding to Affect Collagen Fibril Damage Mechanisms but Not Stiffness

2014 · Gion Fessel, Yufei Li, et al. · PLoS ONE · 151

Skin Advanced Glycation End Products Glucosepane and Methylglyoxal Hydroimidazolone Are Independently Associated With Long-term Microvascular Complication Progression of Type 1 Diabetes

2014 · Saul Genuth, Wanjie Sun, et al. · Diabetes · 145

GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence

2014 · LifeLines Cohort Study Group, Karen M. Eny, et al. · Diabetologia · 50

Glucosepane: a poorly understood advanced glycation end product of growing importance for diabetes and its complications

2013 · Vincent M. Monnier, Wanjie Sun, et al. · Clinical Chemistry and Laboratory Medicine (CCLM) · 72

The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes

2012 · Vincent M. Monnier, David R. Sell, et al. · Journal of Diabetes and its Complications · 57

Advanced Glycation End-Products as Markers of Aging and Longevity in the Long-Lived Ansell’s Mole-Rat (Fukomys anselli)

2011 · Philip Dammann, David R. Sell, et al. · The Journals of Gerontology Series A · 38

Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis

2010 · Xingjun Fan, David R. Sell, et al. · Free Radical Biology and Medicine · 70

Partial characterization of the molecular nature of collagen-linked fluorescence: Role of diabetes and end-stage renal disease

2009 · David R. Sell, Ina Nemet, et al. · Archives of Biochemistry and Biophysics · 28