How do obesity and related inflammation decrease antibody responses in aging?
Description: Aged mice and humans have suboptimal immune responses, e.g. ability to make good vaccine responses, and chronic inflammation and obesity contribute to this. This project investigates the root causes of this inflammation and of defects in antibody producing cells in aging and obesity and provides models for intervention/treatment.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R01
Start date: 2005-02-01
End date: 2023-05-31
Investigator: BONNIE B. BLOMBERG
Institution: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
Funded outputs count: 42
Funder award ID: R01AG023717
OpenAlex ID: G4916740101