Award

G0900582

Funder: Medical Research Council

Funded outputs count: 24

Funder award ID: G0900582

OpenAlex ID: G6990300350

Senescence Markers and Associated Transcriptomic Changes Are Expressed at Early Stages of Alzheimer’s Neuropathology but Are Not Independently Related to Dementia

2026 · Irina Vazquez-Villaseñor, Bridget Benson, et al. · International Journal of Molecular Sciences

VCING Scoring and White Matter Arteriolosclerosis Show Relationships to Dementia Status and White Matter Damage in an Unselected Ageing Brain Cohort

2026 · S. B. Wharton, C. D. Richardson, et al. · Neuropathology and Applied Neurobiology

Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies

2024 · Mohammed D. Rajab, Teruka Taketa, et al. · Brain Pathology · 1

Relationships of brain cholesterol and cholesterol biosynthetic enzymes to Alzheimer’s pathology and dementia in the CFAS population-derived neuropathology cohort

2024 · Hemant Mistry, Connor D. Richardson, et al. · Neuroscience Research · 5

Insights into the pathological basis of dementia from population‐based neuropathology studies

2023 · Stephen B. Wharton, Julie E. Simpson, et al. · Neuropathology and Applied Neurobiology · 26

Assessment of Alzheimer-related pathologies of dementia using machine learning feature selection

2023 · Mohammed D. Rajab, Emmanuel Jammeh, et al. · Alzheimer s Research & Therapy · 19

The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia

2023 · Emma Nichols, Richard Merrick, et al. · The Lancet Healthy Longevity · 108

LATE-NC staging in routine neuropathologic diagnosis: an update

2022 · Peter T. Nelson, Edward B. Lee, et al. · Acta Neuropathologica · 175

Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts

2022 · Peter T. Nelson, Carol Brayne, et al. · Acta Neuropathologica · 175

Assessment of Alzheimer-related Pathologies of Dementia Using Machine Learning Feature Selection

2022 · Mohammed D Rajab, Emmanuel Jammeh, et al. · Research Square · 2

Assessment of Alzheimer-related Pathologies of Dementia Using Machine Learning Feature Selection

2022 · Mohammed D Rajab, Emmanuel Jammeh, et al. · medRxiv · 1

Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer’s and small vessel disease pathologies

2020 · Rachel Waller, Ruth Narramore, et al. · Brain Pathology · 16

Epidemiological pathology of Aβ deposition in the ageing brain in CFAS: addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches

2019 · on behalf of the Cognitive Function and Ageing Neuropathology Study Group, S. B. Wharton, et al. · Acta Neuropathologica Communications · 28

Metallothionein‐I/II expression associates with the astrocyte DNA damage response and not Alzheimer‐type pathology in the aging brain

2018 · Rachel Waller, Mark Murphy, et al. · Glia · 36

TREM2 expression in the human brain: a marker of monocyte recruitment?

2017 · Marie Fahrenhold, Sonja Rakic, et al. · Brain Pathology · 76

Innate immunity in Alzheimer’s disease: the relevance of animal models?

2017 · Diana K. Franco Bocanegra, James A. R. Nicoll, et al. · Journal of Neural Transmission · 31

Microinfarcts in an older population‐representative brain donor cohort (MRC CFAS): Prevalence, relation to dementia and mobility, and implications for the evaluation of cerebral Small Vessel Disease

2016 · P. G. Ince, T. Minett, et al. · Neuropathology and Applied Neurobiology · 54

Microglial immunophenotype in dementia with Alzheimer’s pathology

2016 · MRC CFAS, Thais Minett, et al. · Journal of Neuroinflammation · 219

Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?

2016 · Mariko Taga, Thais Minett, et al. · Brain Pathology · 26

Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study

2016 · on behalf of the MRC Cognitive Function and Ageing Neuropathology Study Group, Stephen B. Wharton, et al. · Acta Neuropathologica Communications · 60

A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment

2015 · Ryan Mathur, Paul G. Ince, et al. · PLoS ONE · 52

Education, the brain and dementia: neuroprotection or compensation? EClipSE Collaborative Members

2010 · Carol Brayne, Paul G. Ince, et al. · Newcastle University ePrints (Newcastle Univesity)