Clinical pilot projects of personalised medicine in the precise prevention of breast cancer and cardiovascular diseases
Description: We propose to carry out pilot projects with two types of diseases using the principles of personalised medicine. One project is the implementation of a model for personalised risk-based breast cancer screening, early detection and prevention. The study is aimed to demonstrate the usability of personalised approach for adjusting screening recommendations, based on predicted genetic and cumulative risk estimates for breast cancer including both the detection of moderate and high hereditary breast cancer risk carriers as well as high risk polygenic risk score carriers among healthy individuals. The other project is the implementation of a model for personalised PREVENTION OF CARDIOVASCULAR DISEASES (CVD) AND MORTALITY. The project is aimed to demonstrate the usability of personalised approach for stratification, adjusting screening recommendations, based on predicted genetic and cumulative risk estimates for CVD among healthy individuals by risk factors calculation and genetic testing.
Funder: Eesti Teadusagentuur
Amount: €1,500,000
Funding type: grant
Funder scheme: Strateegilise TA tegevuse toetamine (RITA1)
Start date: 2018-01-01
End date: 2021-05-31
Investigator: Peeter Padrik
Institution: Tartu University Hospital
Funded outputs count: 0
Funder award ID: RITA1/01-42
OpenAlex ID: G7004583290