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115797

Funded outputs count: 35
Funder award ID: 115797
OpenAlex ID: G7033908404
Engineering the insulin signal peptide to protect human pancreatic beta cells from autoimmune destruction
2026 · Farah Kobaisi, Masaya Oshima, et al. · Cell Reports
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Pancreatic islets: new discoveries for innovative treatments of diabetes?
2026 · Raphael Scharfmann, Arnaud Zaldumbide · Diabetologia
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Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells
2025 · Alexia Carré, Fatoumata Samassa, et al. · Nature Communications · 35
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Structure, interaction and nervous connectivity of beta cell primary cilia
2024 · Andreas Müller, Nikolai Klena, et al. · Nature Communications · 32
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses
2024 · Federica Vecchio, Alexia Carré, et al. · Science Advances · 27
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Tryptophan metabolism promotes immune evasion in human pancreatic β cells
2023 · Latif Rachdi, Zhicheng Zhou, et al. · EBioMedicine · 15
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Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes?
2023 · Decio L. Eizirik, Florian Szymczak, et al. · Nature Reviews Endocrinology · 86
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Coxsackievirus and Type 1 Diabetes: Diabetogenic Mechanisms and Implications for Prevention
2023 · Alexia Carré, Federica Vecchio, et al. · Endocrine Reviews · 62
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In vitro beta-cell killing models using immune cells and human pluripotent stem cell-derived islets: Challenges and opportunities
2023 · Clémentine Halliez, Hazem Ibrahim, et al. · Frontiers in Endocrinology · 2
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Epitope-based precision immunotherapy of Type 1 diabetes
2023 · Rebuma Firdessa Fite, Camillo Bechi Genzano, et al. · Human Vaccines & Immunotherapeutics · 16
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Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet
2022 · Marine De Burghgrave, Chloé Lourenço, et al. · Cells · 7
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The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α
2022 · Vikash Chandra, Hazem Ibrahim, et al. · Nature Communications · 54
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Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation
2022 · Aїsha Callebaut, Ylke Bruggeman, et al. · Frontiers in Endocrinology · 13
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Self-antigens, benign autoimmunity and type 1 diabetes: a beta-cell and T-cell perspective
2022 · Fatoumata Samassa, Roberto Mallone · Current Opinion in Endocrinology Diabetes and Obesity · 15
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Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuits
2022 · Kevin Saitoski, Maria Ryaboshapkina, et al. · Journal of Biological Chemistry · 14
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Personalized Immunotherapies for Type 1 Diabetes: Who, What, When, and How?
2022 · Claire Deligne, Sylvaine You, et al. · Journal of Personalized Medicine · 26
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Regulation of T-Cell Immune Responses by Pro-Resolving Lipid Mediators
2021 · Javier Perez-Hernandez, Valerio Chiurchiù, et al. · Frontiers in Immunology · 45
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Editorial: Footprints of Immune Cells in the Type 1 Diabetic Pancreas
2021 · Todd M. Brusko, Roberto Mallone, et al. · Frontiers in Endocrinology
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A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes
2021 · Sandrine Luce, Sophie Guinoiseau, et al. · Frontiers in Immunology · 14
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PCSK9 affects expression of key surface proteins in human pancreatic beta cells through intra- and extracellular regulatory circuits
2021 · Kevin Saitoski, Maria Ryaboshapkina, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes
2021 · Marie Eliane Azoury, Fatoumata Samassa, et al. · Diabetes · 23
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Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes
2021 · Noémie Corcos, Slobodan Culina, et al. · Frontiers in Immunology · 6
Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?
2021 · Teresa Rodriguez-Calvo, Gustaf Christoffersson, et al. · Frontiers in Immunology · 8
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Making Insulin and Staying Out of Autoimmune Trouble: The Beta-Cell Conundrum
2021 · Alexia Carré, Roberto Mallone · Frontiers in Immunology · 27
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Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes
2020 · Lorella Marselli, Anthony Piron, et al. · Cell Reports · 112
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