Applications of nanofiber needles to Raman-based optical analysis in single cells
Description: Real-time single cell analysis is an important technological milestone that may enable diagnosing cancer or senescence of single stem cells in regenerative medicine. The project is aimed to develop such a single cell analysis in a remote-sensing style for cells in living organisms by using optical nanofibers. We fabricated needle-shape nanofibers by a newly developed hydrogen-oxygen micro torch to form arbitrary shapes of nanofibers. Nanofibers design was conducted by electromagnetic simulation. Raman characteristics and stem-cell function have been evaluated in the context of their integration into nanofiber-based single cell analysis.
Amount: ¥3,770,000
Funding type: research
Funder scheme: Grant-in-Aid for Challenging Exploratory Research
Start date: 2016-04-01
End date: 2019-03-31
Investigator: Masazumi Fujiwara
Institution: Osaka City University
Funded outputs count: 13
Funder award ID: 16K13646
OpenAlex ID: G7055124010